Toxicologist/Discovery Safety Specialist
AstraZeneca AB / Kemistjobb / Göteborg
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hela Sverige Would you like to bring your scientific excellence to Drug Safety and Metabolism at AstraZeneca and become a key player in the discovery of safe innovative medicines? Would you like to apply your expertise in a company that is following the science and turns ideas into life changing medicines?
At AstraZeneca, we are looking to recruit a Toxicologist/Discovery Safety Specialist to strengthen the Safety Science and Discovery team within the Cardiovascular, Renal and Metabolism (CVRM) Safety department. The position may be placed at AstraZeneca's vibrant R&D site either in Gothenburg, Sweden, or in Gaithersburg, Maryland, USA.
Within the CVRM Safety department, part of our global Drug Safety and Metabolism (DSM) function, the Safety Science and Discovery teams develop and apply innovative scientific strategies to drive the design and selection of safe medicines for patients suffering from Cardiovascular, Renal and Metabolic (CVRM) diseases. As true drug hunting partners to the Innovative Medicines units, we contribute to the selection of novel drug targets, design of therapeutic concepts, identification and optimization of different modalities, and the selection of novel candidate drugs. We develop and apply cutting edge molecular, cellular and in vivo technologies to push the boundaries of predictive safety science and investigative toxicology with our mission in mind:
SCIENCE - PASSION - EXPERTISE - Fundamental to selection and delivery of safe and efficacious medicines to patients.
The role
To be successful in this role as Toxicologist/Discovery Safety Specialist we believe that you are a motivated, creative and innovative scientist with a flexible, team-oriented mindset that enjoys solving problems with goal-focused fashion. We also hope that you want to contribute to our open, positive and collaborative work climate.
Within Clinical Pharmacology and Safety Sciences, we put a strong emphasis on talent development. Therefore, you will be able to develop your scientific leadership by working together with leaders in investigative toxicology, drug discovery, cell biology, and predictive safety science. The level of the role can be tailored after your experience and skills.
Main Duties and Responsibilities
* Be responsible for the safety strategy in multi-disciplinary drug discovery project teams.
* Provide scientific leadership to influence project decision making with the aim to deliver molecules with the Right Safety profile.
* Design and build in vitro and in vivo strategies to predict, assess, and mitigate target- and drug-related safety risks and execute through internal and external experimental capabilities.
* Develop innovative solutions and research proposals based on strategic needs of the discovery project portfolio, and to pursue cutting edge science and technologies in order to optimize and influence safety assessment of novel drugs.
* Engage with world-class experts across our organization to develop, refine and implement innovative experimental strategies and use the data to assess and/or provide mechanistic understanding of safety issues.
* Contribute to the discovery of innovative treatments for Cardiovascular, Renal and Metabolic (CVRM) diseases.
Essential requirements
* MSc or a higher degree in toxicology, cell biology, pharmacology, systems biology or related field, and a strong scientific track record. Relevant on the job experience will also be considered.
* Experience with design of strategies and/or execution of in vitro and/or in vivo experiments to determine the safety and/or efficacy of advanced therapeutics (e.g. biologics, oligonucleotide-based therapeutics, AAV or novel delivery systems) will be considered an advantage.
Preferably you have >3 years' experience as a scientist in the drug discovery phase, from project conception to candidate drug selection. Safety experience is considered an advantage and you should be fluent and comfortable communicating, presenting and influencing skills across levels/disciplines.
If this sounds like the job for you, apply today!
We look forward to your application no later than 16th February 2020.
More information
For more information about the position, please contact recruiting manager Mikael Persson (Director, Safety Science and Discovery, CVRM Safety) at
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2020-01-16ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2020-02-13
Klicka på denna länk för att göra din ansökanFöretagAstrazeneca AB
Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-071659".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Arbetsplats AstraZeneca
Jobbnummer 5045444
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