Postdoctoral Scientist - In vivo Precise genome editing
AstraZeneca AB / Biologjobb / Göteborg
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At AstraZeneca we believe in the potential of our people and you'll develop beyond what you thought possible. We make the most of your skills and passion by actively supporting you to see what you can achieve no matter where you start with us.
We are now looking to hire a Postdoctoral Scientist with placement in Gothenburg, Sweden.
The focus of the postdoctoral project is developing new strategies of precise genome editing approaches to apply for target validation, disease modeling and therapy. In particular the postdoc will work with animal model of neurodegenerative diseases and will apply new tools and methods developed in the AZ Precise Genome Editing team.
Essential Requirements
You should have a Ph.D. degree or corresponding experience in a relevant scientific discipline with experience in drug discovery or, alternatively, a first degree and significant relevant experience in drug discovery.
You should have good social and communication skills, be collaborative and a strong team player. You should be able to work independently, take own initiatives and have a positive, goal oriented and problem solving attitude. Good organisational skills are required and you should be comfortable in presenting your results. Excellent English is required, both spoken and in writing.
The following skills are highly desirable
* Expertise with in vivo delivery of viral and/or non-viral vector with particular emphasis with brain delivery
* Molecular biology expertise and manipulation of cell lines, mouse embryonic stem cells, primary, iPSC cells and iPSC derived neuronal lineages.
* Expertise with generation and engineering of 3D cell structure, organoids and Microphysiological systems (MPS)
* Generation and of viral vectors (lentivirus, AAV, Adenovirus) or LNP for in vitro and in vivo genetic engineering
* Functional characterization of gene modified mouse lines or in vivo edited mouse models
* In silico analysis of genetic perturbation after genome editing.
If you are interested, apply now!
For more information about the position please contact: Marcello Maresca at +46317761364
We welcome your application no later than January 31st, 2018.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.
Varaktighet, arbetstid
Heltid Temporary
Publiceringsdatum2018-01-03ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-01-17
Ange följande referens när du ansöker: R-019936
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
Ann-Sofie.Tharna@astrazeneca.comFöretagAstraZeneca AB
AdressAstraZeneca AB
43183
43183 1480
KontorsadressPepparedsleden 1, SE-431 83 Mölndal
Jobbnummer 3882413
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