Postdoctoral fellow in Cell biology

Göteborgs universitet / Apotekarjobb / Göteborg
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The University of Gothenburg tackles society's challenges with diverse knowledge. 37 000 students and 6 000 employees make the university a large and inspiring place to work and study.
Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

At the department of Rheumatology and Inflammation Research, Inflammation is the main topic of the research conducted within the department. Our research groups perform studies of
inflammatory diseases, whether caused by allergy, infection, or autoimmune disease. The goal is to investigate the mechanisms underlying the body's tissues become inflamed.
Many of our researchers are also working as a specialist physician at the clinic at Sahlgrenska University Hospital, which is also one of our greatest assets.
The research group has a focus on inflammatory processes in the central nervous system during viral infection. The work involves cellular, molecular and genetic analysis of patients with
meningitis and encephalitis in combination with a detailed analysis of the immune system in the CNS during experimental infections.

Subject area
Cell biology

Specific subject description
The research group has through exome sequencing identified a number of genes that are mutated in patients suffering from severe complications (meningitis) following infection with the
sexually transmitted virus herpes simplex virus type 2 (HSV-2). The current aim is to study how these mutations affect innate immune responses to HSV-2.

Job assignments
To be responsible for studies of virus-induced signaling pathways in cell-lines and primary cells
after genetic manipulations allowing enhanced or suppressed expression of specific genes or
gene variants. The work involves tissue culture, design of vectors for use in eukaryotic cells, transfection, immunoprecipitation, qPCR, flow cytometry and protein analyses (western blot
etc). In addition, some supervision of master 's students and PhD students is expected as well as teaching/administration of PhD courses, manuscript writing and the ability to attract research
funding.

Eligibility
To qualify as a postdoctoral researcher the applicant should hold a PhD in a relevant subject.
Since postdoctoral constitutes a qualifying appointment for junior researchers, we aim to target
those who have a doctoral degree not older than 3 years from the application deadline.

Assessment
Extensive experience of cell biology research. The applicant should have documented experience of tissue culture, transfection of eukaryotic cells, design of vectors for overexpression of genes, qPCR, immune-precipitation and western blot. Experience with CRISPR/Cas9 and bioinformatics is a merit. The applicant is expected to have written and published articles in cell biology in international peer-reviewed journals.

Appointment Procedure
Please apply online.
Contact information for 2 referee persons should be included in the application.
The University of Gothenburg promotes equal opportunities, equality and diversity.
Salary is determined on an individual basis.
Applications will be destroyed or returned (upon request) two years after the decision of employment has become
final. Applications from the employed and from those who appeal the decision will not be returned.

Varaktighet, arbetstid
Fixed-term employment, 24 months

Publiceringsdatum
2017-01-20

Så ansöker du
Sista dag att ansöka är 2017-02-08
Ange följande referens när du ansöker: PER 2017/7

Företag
Göteborgs universitet

Adress
Göteborgs universitet
Box 100
40530 GÖTEBORG

Kontorsadress
Universitetsplatsen 1

Jobbnummer
3274868

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