Pathologist to Innovative Medicine & Early Development Unit
AstraZeneca Göteborg / Apotekarjobb / Mölndal
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hela Sverige At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We're focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life.
Each and every one of us believes that science has the ability to change lives and that to deliver this takes many people with many skill sets. When we deliver a life-changing medicine, that success comes from the combined efforts of all of our people.
As a Pathologist in AstraZeneca's Innovative Medicine & Early Development Unit (IMED) unit, you will be helping to take new targets and molecules all the way from idea to licensing and beyond, supporting translational questions, patient safety and regulatory requirements. You will be joining an outstanding global team of Pathologists and will have the opportunity to participate in cutting edge drug development in a multidisciplinary environment with strong collaborative culture.
We are looking for a talented, collaborative and highly motivated pathologist with experience in both experimental and toxicologic pathology to join our team in Gothenburg, Sweden as lead pathologist for the Respiratory, Inflammation and Autoimmune (RIA) IMED. As point of contact between RIA and the Pathology department you will be accountable for overseeing pathology related issues and prioritising pathology support to all RIA drug development projects along the entire pipeline. In this role you will have a deep understanding of human respiratory disease biology including molecular mechanisms, as well as relevant efficacy and toxicological models.
Main Duties and Responsibilities
As the Pathology expert for the RIA IMED, you will be required to provide pathology expertise and interact with, advise and influence project leaders, colleagues in Drug Safety & Metabolism and senior management on project related issues that could impact both the project and RIA globally. You will be expected to drive science and technologic development in collaboration with colleagues in research to support innovation in respiratory disease and first in class treatment opportunities.
In particular, responsibilities will include:
• assessing safety and efficacy of novel compounds;
• contributing to study design, data interpretation and integration;
• evaluating the pathology portion of early safety studies;
• designing and evaluating mechanistic and investigative pathology studies;
• conducting pathology peer reviews, hazard characterisation and risk assessment
• communicating findings providing a comprehensive pathology view and making recommendations to key stakeholders.
• Contributing to in vitro and in vivo disease model validation;
• Supporting discovery research programs by providing a comparative and translational pathology view to projects, animal models and biomarkers;
• Accountable for ensuring pathology support to the entire RIA portfolio, including prioritisation, pathology strategy formulation and regulatory interactions.
Essential Requirements
• experience of working in the pharmaceutical industry
• Doctor of Medicine/ Veterinary Medicine (MD/ DVM) or equivalent degree
• Residency or other specialty training in anatomic and/or toxicologic pathology
• Ph.D. in an aligned scientific field -Previous pharmaceutical /CRO /experimental pathology experience
Desirable Requirements
• Post graduate pathology qualification/ certification (e.g. ACVP, ECVP, FRCPath)
• Experience in the evaluation of animal models of human disease with an emphasis on respiratory disease models would be an added benefit.
• Experience in the evaluation of inhalation toxicity studies.
More than ever, science is accelerating our rate of understanding in a wide range of medical fields - and that's only set to increase. As a global, science-led biopharmaceutical business, AstraZeneca is at the forefront of that evolution. That means an unparalleled product portfolio and a strong pipeline across all stages of the drug development process. Everything we do comes back to improving the health of our patients worldwide, and to make that happen we're focusing on some of the most challenging diseases facing humanity today.
We have a highly collaborative culture, where you'll be encouraged to push the boundaries of science while developing industry-recognised skills and experiences.
Publiceringsdatum2017-04-23Så ansöker duSista dag att ansöka är 2017-05-05
Klicka på denna länk för att göra din ansökanFöretagAstraZeneca Göteborg
AdressAstraZeneca Göteborg
Pepparedsleden 1
43183 MÖLNDAL
KontorsadressPepparedsleden 1
Jobbnummer 3453730
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