Senior Scientist - Synthetic/Medicinal Chemistry
AstraZeneca / Logistikjobb / Göteborg
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hela Sverige Are you a skilled Synthetic Chemist dedicated to use your scientific skills to make a difference? Do you enjoy a collaborative and creative working atmosphere? Would you like to join a company where absolutely everyone can thrive?
At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.
This position is placed in the department of Medicinal Chemistry of Respiratory, Inflammation & Autoimmunity (RIA) - right in the middle of AstraZeneca's vibrant R&D site in Sweden.
RIA 's Medicinal Chemistry team is focused on driving discovery research to deliver world-class medicines with an emphasis on small to large sized synthetically accessible molecules. This includes classical small molecules, peptides, oligonucleotides - and Proteolysis Targeting Chimeras (PROTACs). Right now, we are further expanding our portfolio in the PROTAC area. Our team operates in a cross-disciplinary environment in close collaboration with biologists, DMPK experts and Pharmaceutical Scientists to advance the RIA project pipeline.
You will join a highly integrated discovery team leveraging innovative Medicinal Chemistry to invent novel medicines. Your focus will be on synthesis, purification and characterization of lead molecules from target validation to lead optimization - certainly including compound design and Medicinal Chemistry aspects with a focus on PROTACs. You will ensure uptake of novel scientific developments in synthetic Organic Chemistry into project teams and influence compound design by generating completely novel ideas for our molecules.
We are looking for a person with a strong scientific background in Organic Chemistry including excellent verbal and written communication skills and the ability to engage and collaborate across boundaries. We see you as a person with a problem-solving attitude and delivery focus, as well as a strong interest to continuously develop new skills in Medicinal Chemistry. Embedded in a strongly science driven environment, this position certainly includes opportunities to share scientific findings and publish novel science.
Main Duties and Responsibilities
* Actively contribute to RIA 's PROTAC portfolio projects with compound design and synthesis
* Provide state-of-the-art Synthetic Chemistry to projects at all stages of drug discovery
* Deliver high quality drug molecules and tool compounds
* Apply synthetic skills with an idea generation mindset, learning to efficiently troubleshoot Medicinal Chemistry problems while maintaining a clear focus and impact on project progression
* Continuously expand expertise in PROTAC Medicinal Chemistry aspects
* Drive RIA 's scientific reputation by identifying and contributing to publication opportunities internally, across AZ and/or together with external partners
* Follow safety requirements and all AZ corporate responsibility policies
Essential Requirements
You are a creative scientist with a strong synthetic background and the desire to rapidly develop as Medicinal Chemist. We believe that being successful in this position requires:
* PhD in Organic Chemistry, Medicinal Chemistry or Biochemistry
* Excellent skills in Organic Synthesis
* Up-to-date with modern purification and analytical techniques
* Excellent communication and collaboration skills
Desirable Requirements
* Postdoctoral and/or industrial experience is a plus
* PROTAC experience is a significant plus
* Basic knowledge of drug discovery in the pharmaceutical industry is a plus
Are you ready to make a difference? Send in your application, and we'll make it happen together.
For more information about the position please contact:
Lena Ripa, RIA Medicinal Chemistry, at
Welcome with your application no later than June 15th, 2019!
Our Location
Our Gothenburg site is one of AstraZeneca's three strategic science centers. We thrive in a multinational environment working cross-functionally across the globe with AstraZeneca colleagues as well as academic and industry partners. Our way of life is to foster a working environment that nurtures, collaboration, openness and innovation. Therefore, we have created space for meetings, socializing and relaxation, where spontaneous meetings can give birth to new innovations. The unexpected ideas or thoughts that can come from a chat over something as simple as a cup of coffee or a stroll on our "walk and talk" meeting trail.
Our Gothenburg site:
https://www.astrazeneca.com/our-science/gothenburg.htmlLife in Gothenburg:
https://www.movetogothenburg.com/Culture and atmosphere of the Gothenburg site:
https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2019-05-17ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2019-06-14
Ange följande referens när du ansöker: R-051107
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
karin.lyckemalm@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparredsleden 1
Jobbnummer 4794319
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