Head Of Biomarker Discovery Imed Ria Sweden
AstraZeneca / Apotekarjobb / Göteborg
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hela Sverige At AstraZeneca when we see an opportunity for change we seize it and make it happen, because an opportunity no matter how small can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential.
RIA Target & Translational Sciences (TTS) is an agile environment, with a culture that is science and patient-focused. Our mission is to understand disease mechanisms at the molecular level, identify the most effective target and the right patient population, and close the gap between bench science and bedside clinical practice.
A key aspect in translational science is the discovery of biomarkers to drive patient segmentation, demonstrate target engagement, guide dose selection and bridge to clinical outcome. The Head of Biomarker Discovery is accountable for discovery of new respiratory precision and target engagement biomarkers and their development and validation. It is a leadership role that requires a strong scientific background as well as excellent people management and interpersonal skills. The individual will have outstanding team working skills and a consistent track record of working collaboratively to ensure scientific excellence and robust delivery to projects.
Accountabilities and Responsibilities
You will be accountable for the delivery of biomarker discovery platforms and actively exploiting available omics-initiatives, both internal or and external, to discover and develop novel, innovative biomarker propositions. Agnostic to platform, you will drive discovery through established and new technologies, including genomics, transcriptomics, proteomics, metabolomics, epigenomics, lipidomics etc.
Working closely with TTS colleagues, you will play a pivotal role in:
* The identification of novel biomarkers for patient segmentation, demonstration of target engagement and the bridge to clinical outcome.
* Extracting knowledge from big omics-datasets
* Working with the AZ Genomics Initiative to ensure new studies are requested, results are brought into TTS, and that new putative targets are prosecuted.
* The use of experimental medicine studies to identify novel biomarkers and support recall by genotype clinical study design.
You will select, develop, retain and motivate your team of Biomarker Scientists. Together, you will drive innovation and scientific excellence in Biomarker Discovery through internal scientific development and external collaborations. You will manage resources so that the demand for new biomarkers is met in a flexible, competent and responsive manner. This includes proposing, establishing and leading external collaborations related to your area of expertise. You will plan and develop Biomarker Discovery in close collaboration with Department Head and the other TTS leaders.
Building and maintaining a work environment in which scientific challenge and innovation are maximised, you will work collaboratively with other Teams within and outside of the Innovative Medicines and Early Discovery Biotech Unit and make AstraZeneca scientifically visible by publishing scientific papers and presenting data at conferences.
Minimum Requirements
* PhD/post-doc in life sciences or other relevant area, alternatively MD with research background
* Proven leadership and delivery in biomarker discovery, biomarker platforms and application to drug discovery and precision medicine
* 10 years of work experience in pharmaceutical R&D, preferably discovery and development
* Strong leadership skills and ability to be a self-starter
* Experience and deep understanding of biology, pharmacology, translational medicine and clinical sciences, with pre-eminence in at least one of these areas
* A solid understanding of the drug development process, from lead identification through clinical development
* Excellent written, oral, presentation and interpersonal skills
* Ability to work productively in a matrix team environment
* Experience in the Respiratory therapy area preferable
If you are interested, apply now!
For more information about the position please contact Adam Platt,
Welcome with your application no later than October 14th, 2018.
For more information about life in Gothenburg visit
www.movetogothenburg.com Our Respiratory research is mainly carried out at the vibrant AstraZeneca Research site in Gothenburg, Sweden. However, collaboration is a way of life for us. Extensive collaboration with our AstraZeneca colleagues in Cambridge UK, the MedImmune research units in Gaithersburg and Cambridge, as well as numerous academic institutions and partners around the globe gives us access to a worldwide network of expertise and innovation.
Our external collaborators expand both academic and biotech organisations including Imperial College London, Pieris, Bicycle Therapeutics, Ethris and many more. We aim to be flexible, responsive, open and honest and look for people, companies and investigators who share our collaborative spirit and high scientific standards.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2018-09-13ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-10-11
Ange följande referens när du ansöker: R-032620
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
karin.lyckemalm@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparredsleden 1
Jobbnummer 4346046
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