Senior Scientist, In Vitro Cardiovascular Biology
AstraZeneca / Biologjobb / Göteborg
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hela Sverige Do you have expertise in in vitro biology within the Heart Failure and Cardiovascular disease area and enjoy working in the lab? Would you like to apply your expertise in a company where we are following the science and turn ideas into life changing medicines? Then you might be the one we are looking for!
We are now recruiting a Senior Scientist, in vitro biology with focus on heart failure and cardiovascular disease to join the heart failure in vitro team within the Cardiovascular, Renal and Metabolism (CVRM) therapeutic area at AstraZeneca in Gothenburg, Sweden.
Business area CVRM IMED: CVRM is one of the three main therapeutic research areas within Innovative Medicines and Early Development (IMED), AstraZeneca's Biotech unit that deliver candidate drugs into clinical development. AstraZeneca has a patient-centric approach for discovering novel treatments for patients with metabolic disease, chronic kidney disease and cardiovascular disease and the three areas are integrated into one unit - CVRM IMED. At the Bioscience Heart failure department we focus on identifying and validating new drug targets for patients with cardiovascular disease and heart failure. The team delivers key data to projects across all phases of the drug discovery and development and we work with different modalities such as small molecules, modified mRNA, antisense oligonucleotides (ASOs) and peptides.
The Role: As a Senior Scientist in the Heart Failure in vitro team, you will play a key role in progressing science and projects. This role is primarily lab-based and you will explore novel drug targets and support existing projects with key in vitro and ex vivo data. You will also develop new in vitro assays and models for heart failure to support the projects and the heart failure strategy. Collaboration is critical for successful delivery of drug projects and you will work closely with scientists/teams from a wide range of different functions within AstraZeneca as well as with external partners and collaborators. You will work with in vitro biology using induced pluripotent stem cells (iPSC) and primary cardiovascular cells along with molecular biology techniques and high content imaging. In this role, you will have the opportunity to try novel techniques and ideas required for progressing existing portfolio and novel science.
Main Duties and Responsibilities
* Independently design, develop and execute in vitro and ex vivo assays for projects from pre-target identification to clinical stage
* Independently analyse and interpret generated data and perform basic statistical analyses
* Maintain deep understanding of the science in heart failure and cardiovascular medicine area
* Presentation of data to the project team, department, science board and at external meetings
* Contribute to communications of scientific findings through publications in scientific journals and meetings
* Work collaboratively within Bioscience and other functions throughout AstraZeneca to deliver on key project activities
* Contribute proactively to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared
Essential Requirements
* Master's degree or equivalent academic merits in cell and molecular biology, physiology or biochemistry or similar and experience of working with cardiovascular disease
* Strong experience in cell based assays and molecular biology
* Experience with functional readouts, such as contractility or metabolism, in cell systems
* Knowledge and experience in handling and manipulating relevant cardiac cell types, including iPS cells and primary cardiac cells
* Entrepreneurial ways of working
* Good collaboration skills
* Strong oral and written communication skills
* Excellent English, both spoken and in writing
Desirable Requirements
* PhD in a relevant field
* A strong scientific background and publication track record in any of the following fields: cardiac regenerative medicine, cardiac metabolism, cardiovascular disease, heart failure, cardiac stem cell biology or angiogenesis
* Background in drug discovery and development in the pharmaceutical industry
If you are interested, apply now!
For more information about the position please contact Karin Jennbacken at +46-31-7065115
Welcome with your application no later than 29 October, 2018.
AstraZeneca is a global, innovation-driven pharmaceutical company focusing on the discovery, development and commercialization of novel medicines. At AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration both within the company and with external partners. Employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2018-10-15ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-10-29
Ange följande referens när du ansöker: R-037367
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
ulrica.marklund1@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparedsleden 1
Jobbnummer 4403802
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