Senior Clinical Pharmacometrician

AstraZeneca AB / Kemistjobb / Göteborg
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Do you have expertise and experience in mathematical modelling and simulation, PKPD and its application in drug development? Would you like to apply your expertise in a company that is following the science and turn ideas into life changing medicines? Then you might be the one we are looking for!

This is an opportunity for a talented and engaged individual to join our growing Clinical Pharmacology and Quantitative Pharmacology team at AstraZeneca in Gothenburg and develop as a Clinical Pharmacometrician supporting large and small molecule projects across full development within the therapy area of Cardiovascular, Renal and Metabolism.

AstraZeneca is a world-leading pharmaceutical company, we focus on discovering and developing medicines that make a real difference to millions of patients. In the role as Clinical Pharmacometrician you will be working closely with clinical pharmacology scientists, physicians and other scientists, you will apply modelling to support the design and interpretation of clinical studies and influence key decisions in early and late clinical development.

Within the Clinical Pharmacology and Safety Sciences (CPSS) function, we have a state-of-the-art quantitative clinical pharmacology group with a diverse and uniquely skilled team of clinical pharmacometricians and clinical pharmacology scientists, and in Gothenburg two of our key therapeutic areas are located. You will thrive in an environment that inspires innovation, encourages multidisciplinary team-working and collaboration with academia, and rewards original scientific thinking.

Main duties and responsibilities

The work includes integration of relevant data, such as dose information, pharmacokinetics, biomarkers and clinical endpoints within and across studies, compounds and development stages. Support to informative trial designs using simulations and efficient modeling statistics is an important focus area for us. In collaboration with clinical pharmacology scientists, you will represent Clinical Pharmacology and Quantitative Pharmacology and be responsible for identifying and executing modelling to support model informed drug development. You will communicate your findings to other scientists within and outside of AstraZeneca and publish them in peer reviewed journals.

Essential Requirements

* Quantitative modelling skills, e.g. knowledge in mathematics and statistics applied to life sciences
* Background and an understanding of clinical pharmacology aspects of drug development, preferably in both the small and large molecule setting
* Working knowledge of pharmacokinetics and its clinical application
* Biological understanding of disease and drug action
* Good oral and written communication skills

Desirable requirements

* Recognised scientific expertise demonstrated by scientific publishing in the field of clinical pharmacology
* Early or late phase clinical development experience/awareness.

If this sounds like the next step for you - apply now!

For more information about the position please contact recruiting manager Bengt Hamrén at +46 31 7762201.

Welcome with your application no later than January 31, 2020.

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2019-12-19

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2020-01-16
Klicka på denna länk för att göra din ansökan

Företag
Astrazeneca AB

Arbetsgivarens referens
Arbetsgivarens referens för detta jobb är "R-069037".

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Astrazeneca AB (org.nr 556011-7482)

Arbetsplats
AstraZeneca

Jobbnummer
5012562

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