PostDoc Fellow - Autophagy, Viral Infection & Antiviral Immunity
AstraZeneca Göteborg / Apotekarjobb / Mölndal
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hela Sverige Our Respiratory, Inflammation and Autoimmunity team offers definitive expertise to colleagues across the business. You'll help patients in areas with medical needs that aren't being fully met, including chronic obstructive pulmonary disease, asthma and rheumatic disorders. Right now, we're a leading figure in inhaled drug development, and our new Inhalation Centre in Gothenburg, Sweden is set to extend that lead even further.
Main duties and responsibilities
PostDoc long title: The Role of Autophagy in Rhinovirus Replication and Innate Antiviral Immunity in Chronic Lung Diseases
This is an exciting opportunity to join a team dedicated to the study of lung epithelial host defence. The aim of the project is to explore novel mechanisms in host-virus interactions and innate immunity, with a particular focus on the role of autophagy. A unique aspect of the project is the possibility to study the impact of these events in chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD), using patient-derived material. Throughout the project, you'll have the opportunity to gain extensive experience in performing live rhinovirus infection of primary human airway epithelial cells, as well as the use of state-of-the art molecular, biochemical and imaging methodologies to track the viral infection and evaluate the host cell response.
You'll drive the project independently while being an integral part of a multidisciplinary team with an extensive range of skills and knowledge from which to learn. Access to state-of-the-art laboratory equipment and technologies will also be provided. You'll be expected to present your results at internal seminars and external scientific conferences, and publish your data in high quality peer-reviewed journals.
Essential requirements
PhD and/or MD in biological science, with a good understanding of virology and innate immunity
Experience using techniques in molecular biology, biochemistry and virology
A genuine commitment to medical science
Strong organisational and interpersonal skills
A proven track record of work published in reputable scientific journals.
Desirable requirements
Knowledge and experience in the field of autophagy
Experience in the culture of primary human airway epithelial cells
Experience of confocal microscopy
Experience of developing and executing in vivo studies.
At AstraZeneca, we believe in the potential of people who share our passion for science. By thinking boldly and working collaboratively to pursue discoveries beyond imagination, you'll develop further and faster than you thought possible. We'll complement your drive and determination to meet unmet patient needs around the world with the inspiration and opportunities to enhance your niche expertise and build your skills. So if you're curious about what science can do, come and make a difference.
As a world leader in cardiovascular and metabolic medicines, we're always working on innovative new drugs that will change lives across the globe. To make that happen, we've divided our small molecule research strategy into three priorities: cardiac regeneration, islet health in diabetes and diabetic nephropathy. You'll focus your efforts on making real progress toward slowing, stopping or curing some of the most aggressive diseases that face humanity today.
Publiceringsdatum2017-02-27Så ansöker duSista dag att ansöka är 2017-04-17
Klicka på denna länk för att göra din ansökanFöretagAstraZeneca Göteborg
AdressAstraZeneca Göteborg
Pepparedsleden 1
43183 MÖLNDAL
KontorsadressPepparedsleden 1
Jobbnummer 3343287
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