Modelling & Simulation Scientist
Adecco Sweden AB / Kemiingenjörsjobb / Södertälje
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hela Sverige Adecco is the largest recruiting and staffing company in the world. Adecco Life Science is one of our specialized Business Lines, which works exclusively with Staffing Services and Recruitment of personnel for the Life Science industry. Our customers are within the Pharmaceutical-, Biotech- and Medtech companies. We focus on positions within Regulatory Affairs, Medical Affairs, R&D, QA, QC, Clinical Research, Marketing and Sales. We are now recruiting a Modelling & Simulation Scientist, located at AstraZeneca, Södertälje. Preferably the candidate start as soon as possible and the assignment will initially continue for nine months.
Description
This temporary role as Modelling & Simulation (M&S) scientist will help provide projects with understanding and integration of the correlation between in-vitro and in-vivo ADME properties and the relationship between pharmacokinetics (PK) / toxicokinetics (TK) and pharmacodynamic (PD) responses including biomarkers for mechanism of action.
Major responsibilities
• Define and deliver on the preclinical and translational PKPD strategy for efficacy and safety, in projects from prior to Target Identification to LCM
• Design preclinical and forward/backward translational PKPD and TKPD studies and report results and interpretations to project teams
• Deliver drug-drug interaction predictions and risk assessments to project teams
• Contribute to estimation of safety margins and make recommendations and predictions on human efficacious dose and exposure
• Evaluate and interpret PKPD and TKPD data to prepare for internal governance bodies
• Work collaboratively with other functions as needed to deliver the above (eg bioscientists, translational scienctists, safety scientists clinical pharmacologists and pharmacometricians).
• Document the work according to AstraZeneca GLS standards
• Contribute proactively to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared.
Key Deliverables
Deliver the PK, DDI, PKPD and TKPD elements to project teams within the agreed timelines and to the right quality
Minimum Requirements
• PhD or equivalent experience in quantitative PK and PD related modelling & simulation of biological systems, ideally in preclinical/translational setting
• Track record of defining quantitative modelling strategies
• Track record of ability to meet timelines to pre-specified quality and cost
• Specialist in modelling and simulation tools such as WinNonLin/Pheonix, Matlab, SIMCYP
• Understanding of integrative aspects of DMPK and pharmacology/safety aspects of drug discovery and development
• Experience in pharmaceutical R&D
• Experience in operating cross-functionally
Skills and Capabilities
Passion for Customers
Thinks Strategically
Acts Decisively
Drives Performance
Works Collaboratively
Develops People and Organisation
What do we offer?
Adecco is the world's largest recruitment and staffing company and our most important asset is our qualified employees. With us, and on our customer assignments, you, as a consultant, will be appreciated for your difference-making competence! Your bank of experience will grow, as will your social and professional network of contacts. Adecco can offer you the opportunity of interesting assignments at attractive companies, of positions that perhaps never will be put on the open market.
We want you to feel good and will give you subsidies for preventive healthcare and discounts on training cards. In order for you to feel secure, you will also be covered by insurance and corporate healthcare.
Are you interested?
Then you should apply as soon as possible. The position is to be filled immediately, and, for that reason, work with recruitment is being done on a continual basis during the application period.
We look forward to your application!
Publiceringsdatum2013-10-30Arbetstider och omfattningFull time
ErsättningAccording to agreements
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Ansökan kan tyvärr inte göras via e-post.
Klicka på denna länk för att göra din ansökanKontaktJenni Sventoft 08-598 98129
FöretagAdecco Sweden AB
AdressAdecco Sweden AB
Kungsgatan 60
10224 STOCKHOLM
Jobbnummer 1690180
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