Cheminformatics Specialist - Hit Discovery, AstraZeneca

AstraZeneca AB / Kemistjobb / Göteborg
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Are you a Cheminformatics Specialist with an interest in working closely with chemists and biologists in a hit identification environment? Would you like to make use of your informatics skills to provide expert advice and push the boundaries of science to make a change? If so, join our journey to develop and deliver novel medicines!

As our new Cheminformatics Specialist you will be a part of the Hit Discovery department in Discovery Sciences. The role has covers new technology development and application in the area of hit identification and automated chemistry and has a special focus on supporting our DNA-encoded libraries team in medicinal chemistry. You will be based at AstraZeneca's R&D site in Gothenburg, Sweden or Cambridge, UK.

Discovery Sciences is part of the global BioPharmaceuticals organisation and provides scientific support to early drug discovery across the global discovery portfolio. The Hit Discovery department is responsible for the discovery of novel chemical hits in four principal areas: High-throughput screening, Fragment-Based Lead Generation, DNA-encoded libraries, and Virtual Screening, augmented by automated chemistry and AI/machine learning.

What you'll do:
Apply and adapt cheminformatics software and science in the fields of DNA-encoded libraries, automated chemistry and Virtual Screening to support compound and data handling, reaction informatics, analysis and learning from data. Other key elements in the role as Cheminformatics specialist include the exploitation and adaptation of cheminformatics technology to support the work and the data handling of chemists and biologist in hit discovery and automated chemistry.

You will provide expert advice and interpretation of complex data and devise, champion and develop the scientific area of Cheminformatics that aligns with the Hit Discovery department mission.

Essential in the role:

* PhD in the area of Cheminformatics or Computational Chemistry with several years of experience combined with profound technical skills like computer programming and systems design, or a degree in Computer Sciences with demonstrated additional knowledge and experiences in a relevant area of science, as chemistry, physics, or biology.
* Demonstrated experience with a variety of software tools and technologies (e.g., Java, C++, Python/Ruby/Perl, SQL, or AWS).
* Experience within a research-based scientific computing environment.
* Excellent knowledge of modern computational chemistry/computer science methods and algorithms and its use in drug hunting projects.

You should also be able to work and collaborate in a multidisciplinary research matrix environment, as well as providing scientific insights. A good understanding of how the drug discovery process functions within discovery and how computational methods contribute to and influence projects is a plus.

Why AstraZeneca?
Be part of a dedicated Research & Development team. Fuelled by our commitment to help more patients, strengthen our pipeline and grow our area. Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

So, what's next? If this sounds like the job and place for you to make a change - apply today!

We look forward to get to know you better. Please send your application to us no later than 16th April. 2023.

For more information about the position please contact hiring manager Jens Sadowski at +46 31 7762850.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Our Cambridge site: https://www.astrazeneca.com/our-company/our-locations/cambridge.html
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html

This position entitles competitive salary and benefits package on offer.

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2023-04-17
Klicka på denna länk för att göra din ansökan

Arbetsgivarens referens
Arbetsgivarens referens för detta jobb är "R-163034".

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Astrazeneca AB (org.nr 556011-7482)

Arbetsplats
AstraZeneca

Kontakt
AstraZeneca
antonia.reimers@astrazeneca.com

Jobbnummer
7614862

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