Bioanalysis Scientist Dmpk To Astrazeneca
Alten Sverige AB / Kemiingenjörsjobb / Göteborg
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hela Sverige About AstraZeneca:
AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. Within this environment employees are empowered to express diverse perspectives, and are made to feel valued, energized and rewarded for their ideas and creativity.
The Arena:
Cardiovascular, Renal and Metabolism (CVRM) is one of the three main therapeutic research area within Innovative Medicines and Early Development (IMED) which deliver candidate drugs into late-stage clinical development. CVRM is based in AstraZeneca's world-class vibrant R&D center, located in Gothenburg, Sweden. CVRM DMPK interacts with other functions in supporting CVRM projects all along the value chain, from target selection all the way to market launch and Life cycle management.
Now we are looking for a bioanalytical scientist with in depth knowledge in the area of quantitative bioanalysis of drugs and drug metabolites to join our team in the CVRM DMPK department for a consultant assignment. The team you will be part of is focusing on metabolism, biodistribution and disposition of small molecule, conjugated peptide and nucleotide drug candidates. You will have the opportunity to contribute to the discovery of new life changing medicines for patients and demonstrate and witness what science can do.
Tasks and responsibilities:
You will be responsible for analysing drug candidates and their metabolites in various in vitro and in vivo samples including plasma, tissue, and bile samples as well as sub-cellular fractions. Your responsibility will include delivering quality in vitro and in vivo bioanalytical data including analysis of drugs, drug candidates and drug metabolites in various in vitro and in vivo samples to support PKPD (Pharmacokinetics and Pharmacodynamics) and biotransformation work in projects from target selection to LCM (life cycle management). The data generated is mainly aimed to provide insight to quantitative pharmacology as well as to right tissue and right exposure aspects, including the fates of drugs and their metabolites.
This laboratory based scientific role includes developing and validating methods to enable delivery of data with the necessary quality and scientific information aligned with the project needs. The role requires interactive, effective communication to provide clear data and guidance to project representatives, act as an example to other scientists, and contribute to the overall team delivery. It will require making judgements about bioanalysis information, developing innovative solutions and applying cross-disciplinary understanding.
Minimum requirements and key factors:
• M.Sc or equivalent degree in a relevant discipline is required
• Track record of delivering state-of-the-art bioanalysis data to projects in discovery and/or development setting
• Good knowledge of liquid chromatography and mass spectrometry ionization and detection (LC-MS/MS) and bioanalytical work in Drug Discovery & Development
• Basic understanding of DMPK
• Understanding of the overall drug discovery and development process
• Good communication skills in English, both verbal and in writing are required
• Demonstrated ability to work in team and independently
Varaktighet, arbetstid
Heltid Tillsvidareanställning
Publiceringsdatum2019-01-22ErsättningEnligt överenskommelse
Så ansöker duSista dag att ansöka är 2019-01-29
Klicka på denna länk för att göra din ansökanKontaktHR-avdelningen, Alten
FöretagAlten Sverige AB
AdressAlten Sverige AB
Theres Svenssons gata 15
41755 Göteborg
KontorsadressTheres Svenssons gata 15, Göteborg
Jobbnummer 4570003
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