Senior Scientist, Translational Biomarkers
AstraZeneca / Apotekarjobb / Göteborg
Observera att sista ansökningsdag har passerat.
Visa alla apotekarjobb i Göteborg,
Mölndal,
Partille,
Kungälv,
Lerum eller i
hela Sverige Visa alla jobb hos AstraZeneca i Göteborg,
Södertälje,
Stockholm eller i
hela Sverige Do you have expertise in Biomarker analysis and assay development in Cardiovascular and Metabolic Diseases? Would you like to apply your expertise at a company that are following the science and turn ideas into life changing medicines? Then you might be the one we are looking for!
We are now recruiting a Senior Scientist, Translational Biomarkers to join the Translational Science (TS) department within the Cardiovascular and Metabolic Diseases (CVMD) therapeutic area at AstraZeneca in Gothenburg, Sweden.
CVMD is one of the three main therapeutic research areas within Innovative Medicines and Early Development, AstraZeneca's small molecule biotech unit that deliver candidate drugs into late-stage clinical development. CVMD TS has the remit to bridge pre-clinical, early and late drug development by providing early target validation in human and by driving precision medicine approaches through biomarker research based on understanding of human diseases and access to human patient samples.
As a Senior Scientist in the Translational Biomarkers team you will be part of a creative and flexible team that investigates novel therapies for heart failure, diabetes, non-alcoholic steatohepatitis (NASH) and, chronic kidney disease by biomarker research.
Main Duties and Responsibilities
The successful candidate will be lab based and contribute to building the biomarker strategy in the projects to generate human target validation and precision medicine approaches. You will be responsible for delivering high quality and robust biomarker data package (target engagement, and proof-of mechanism) to support project progression across the CVMD project portfolio. This involves implementation of novel biomarker methods (e.g. ligand binding techniques, and / or mass spectrometry based approaches) using state of the art analytical techniques, biomarker analysis, evaluation and reporting biomarker data to the project teams.
The role requires interactive, effective communication providing clear data and interpretations to projects and contribution to the translational scientific strategy. You will make judgements about complex scientific information, developing innovative solutions and applying comprehensive cross-functional understanding.
Essential Requirements
* Ph.D. in a relevant scientific discipline and 3-5 years post-doctoral or industrial experience
* Deep expertise in a range of analytical techniques for biomarker analysis, specifically immunoassay/ELISA platforms (MSD, Gyros, Luminex etc)
* Broad experience in mass spectrometry for analysis of biomarkers (proteins, peptides, lipids, small molecules)
* Deep experience in development of novel bioanalytical methods for quantification of biomarkers across CVMD projects
* Ability to: (i) identify novel approaches and technologies that would improve our support to projects, (ii) perform problem solving studies by identification of issues and where necessary designing experiments to overcome problems, (iii) maintain awareness of relevant areas of research, drug discovery/development technologies and regulatory requirements through reading scientific literature and guidelines
* A Passion for delivering and promoting excellence in science.
* Good project management and matrix leadership skills. Ability to collaborate well cross functions.
* An excellent publication track record in the field.
* Excellent English, both verbal and written
Desirable Requirements
* Working knowledge in biology of cardiovascular and metabolic diseases
* Working knowledge in omics technologies such as proteomics, transcriptomics, and metabolomics
* Experience of leading biomarker efforts aligned to drug discovery
* Experience of biostatistics, multivariate data analysis, and statistical learning
If you are interested, apply now!
For more information, please contact hiring manager: Pia Davidsson +46 (0)706 72 88 93 or
Welcome with your application no later than December 18, 2017.
AstraZeneca is a global, innovation-driven pharmaceutical company focussing on the discovery, development and commercialization of novel medicines. At AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration both within the company and with external partners. Employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2017-12-06ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2017-12-27
Ange följande referens när du ansöker: R-017427
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
asa.lothigius@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparedsleden 1
Jobbnummer 3839783
Observera att sista ansökningsdag har passerat.