Senior Research Scientist - NGS/Transcriptomics

AstraZeneca AB / Kemistjobb / Göteborg
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Are you motivated by challenging the boundaries of science? Would you like to contribute directly to AZ's strategy of growth through Innovation? At AstraZeneca we win through science, it's at the heart of our every success. That science is only possible when we all work together - we will always make sure you are clear about how your role is connected to our wider mission to really show what science can do.

Welcome to join us at our R&D site in Gothenburg, Sweden, where we are looking for a Senior Research Scientist with NGS/Transcriptomics expertise.

The position as Senior Research Scientist NGS/Transcriptomics requires significant experience in NGS laboratory practice, additionally the individual will have outstanding team working skills and a proven track record of working collaboratively to ensure scientific excellence and robust delivery to science projects.

The NGS/Transcriptomics team is a creative group working on the development and application of nucleic acid "omics" technologies and processes to generate smart data that will enrich our understanding of drug pharmacology, target mechanisms, model systems, patients and disease. The work is fully aligned with AstraZeneca's strategy of Growth through Innovation.

Main Duties and Responsibilities:

This role is for a scientific specialist in the NGS/Transcriptomics area - a hands-on lab-based role at the forefront of NGS/Transcriptomics technology with a focus on effective delivery, troubleshooting and putting ideas into action. You will bring your current expertise, in one or multiple of the following areas; NGS automation, high throughput transcriptomics, Single cell sequencing, ChIP-seq or long-read sequencing technologies which you will apply to a wide range of clinical and preclinical projects across a range of diseases, species and drug modalities.

We will rely on you to:

* Have significant specialist expertise within the NGS/Transcriptomics field with proven expertise in applying this to scientific projects
* Take a lead in the planning and execution of NGS projects
* Adopt innovative NGS/Transcriptomics processes developed by the team
* Build strong collaborative relationships with the project investigators, key stakeholders, project bioinformaticians and data scientists to ensure the smooth running of projects
* Provide disciplinary scientific leadership and represent the department at interdisciplinary meetings internally as well as externally
* Perform all work in accordance with Safety Health & Environment requirements and in compliance with all AstraZeneca Corporate responsibility policies
* Develop an overall knowledge of the pharmaceutical industry in the global context and the ability to translate this into new business opportunities.

Essential Requirements:

* Ph.D. degree or corresponding experience in a relevant scientific discipline
* Specialist expertise in any of the following: NGS automation, high throughput transcriptomics, Single cell sequencing, ChIP-seq or long-read sequencing technologies
* Broad experience with a range of Next Generation Sequencing /Transcriptomics technologies including RNA-Seq, DNA-Seq, genotyping methodologies
* This experience will cover all relevant aspects from hypothesis generation, through experimental design and execution, RNA and DNA extraction, sample and library preparation, sequencing, data handling, post sequencing QC and trouble shooting.
* Several years of research experience in Pharma/Biotech, medical or academic institutions
* A track record of peer-reviewed high-quality publications and scientific presentations
* Excellent organizational and communication skills.

Desired qualifications:

* Experience in platforms that bridge single gene qPCR to large scale deep sequencing.
* A proven understanding of statistics, quantitative data analysis, data mining and knowledge of LIMS systems

If this sounds like the job for you - apply today!

For more information about the position please contact Graham Belfield at +46 708 808733 or

Welcome with your application no later than 13th January 2020.

Additional information:
Visit our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg and Sweden: https://www.movetogothenburg.com/

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2019-12-19

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2020-01-09
Klicka på denna länk för att göra din ansökan

Företag
Astrazeneca AB

Arbetsgivarens referens
Arbetsgivarens referens för detta jobb är "R-069024".

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Astrazeneca AB (org.nr 556011-7482)

Arbetsplats
AstraZeneca

Jobbnummer
5011379

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