Researcher

Göteborgs universitet / Biologjobb / Göteborg
2018-09-25
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The University of Gothenburg tackles society's challenges with diverse knowledge. 38 000 students and 6 000 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell - what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them. At present, the institute has about 360 employees and approximately 400 million SEK in total assets. The Institute is composed of the following five departments: the Department of Infectious Diseases, the Department of Microbiology and Immunology, the Department of Pathology and Genetics, the Department of Clinical Chemistry and Transfusion Medicine and the Department of Medical Biochemistry and Cell Biology.

Dr. Clausen's research group is interested in elucidating the molecular mechanism of genome instability and DNA repair. In particular, we are interested in understanding how DNA lesions and mutations are generated and are being repaired on a genome-wide, strand specific scale at single nucleotide resolution level. The group will use interdisciplinary approaches to map and characterize ribonucleotide incorporation in DNA.

Recent publications:

Clausen AR, Lujan SA, Burkholder AB, Orebaugh CD, Williams JS, Clausen MF, Malc EP, Mieczkowski PA, Fargo DC, Smith DJ, Kunkel TA. Tracking DNA replication in vivo using ribonucleotides. Nat. Struct. Mol. Biol. 2015; 22:185-91. PMID: 25622295.

Berglund AK, Navarrete C, Engqvist MK, Hoberg E, Szilagyi Z, Taylor RW, Gustafsson CM, Falkenberg M, Clausen AR. Nucleotide pools dictate the identity and frequency of ribonucleotide incorporation in mitochondrial DNA. PLoS Genet. 2017. 16;13(2):e1006628. PMID: 28207748.

26: Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A. Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired. Proc Natl Acad Sci U S A. 2017;114(47):12466-12471. PMID: 29109257.

Job assignments

To process, analyze, interpret and visualize Next-gen sequencing data. Script writing to facilitate the analysis of our data. Expertise in large data handling, processing, analysis, interpretation and visualization using python, R or perl.

Qualifications

PhD in bioinformatics or related areas. Excellence in research and communication. Must be well organized and able to manage several projects with priority.

Employment

The employment is limited (temporary) for 12 months and full-time with placement at the Institute of Biomedicine. First day of employment as agreed.

For further information regarding the position

Please contact Research Fellow Anders R. Clausen. E-mail:anders.clausen@gu.se

Unions

Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The application should contain proof of completed PhD, list of publications and 3 references.

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.



In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

Varaktighet, arbetstid
Visstidsanställning på 12 månader Heltid

Publiceringsdatum
2018-09-25

Ersättning
Universitetet tillämpar individuell lönesättning.

Så ansöker du
Sista dag att ansöka är 2018-10-15
Klicka på denna länk för att göra din ansökan

Företag
Göteborgs universitet

Adress
Göteborgs universitet
Box 440
40530 Göteborg

Kontorsadress
Meidicinaregatan 9A

Jobbnummer
4365166

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