Medicinal chemists/chemical biologists (two positions)
Karolinska Institutet, Institutionen för medicinsk biokemi och b / Kemistjobb / Stockholm
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Division
Within the Division of Translational Medicine and Chemical Biology (Helleday laboratory), Department of Medical Biochemistry and Biophysics, Karolinska Institutet, the physical location will be at Science for Life Laboratory (SciLifeLab) Stockholm.
Our vision, within the Helleday Laboratory, is to translate the findings from our basic research programmes on DNA repair and survival mechanisms within cancer cells, to identification of novel anticancer targets and development of anti-cancer drugs with minimal side-effects.
Our goal is to develop our hypotheses in preclinical models, and then proceed to study the effect and underlying mechanisms of new cancer treatments in patients. In order to do this, we have created an integrated translational strategy, with teams of scientists from a variety of disciplines taking our basic findings all the way from bench to bedside.
We are working in a dynamic research environment, which is well positioned to take advantage of the state-of-the-art platforms at SciLifeLab, we have several established and fruitful collaborations with Stockholm and Uppsala universities and many of our researchers have experience both from academia and the pharmaceutical industry. We are based at SciLifeLab, Karolinska Institutet, where we perform high-throughput screening, basic molecular and cell biology, biochemistry, systems biology, pharmacology and medicinal chemistry.
Today the research group consists of around 30 people. We now wish to expand this number with another 8-10 scientists to meet the ambitious milestones we have set for the next few years.
For a more comprehensive description of our different projects and an overview of our group, please visit our website
www.helleday.orgDuties & Entry requirements
You will have a strong background in medicinal chemistry, chemical biology or synthetic organic chemistry. Some previous experience in drug discovery and optimization of chemical starting points is of merit as is knowledge of molecular modeling and/or computational chemistry. Importantly, you are a highly motivated scientist with the ability to work well in a fast paced multidisciplinary environment. You possess a demonstrable flair for synthetic work and interpretation of SAR, which you can apply to the iterative design of analogues with improved drug-like properties.
The successful applicants will primarily be involved in the synthesis and design of novel anti-cancer compounds, managing, interpreting and reporting data to the project team. The work will be performed in close collaboration both with other academic research groups and clinicians in Sweden and therefore, the ability to communicate well in English (both oral and written) is highly desirable. In addition to actively participating in research projects, some teaching duties may be required. The successful candidates should have excellent interpersonal and cooperation skills, be flexible and capable of working in a structured and efficient way. The successful candidates should also be able to contribute to the innovative and entrepreneurial climate existing within the group.
Karolinska Institutet promotes equality and values the qualities that ethnic and cultural diversity can bring to the university.
Employment form: two year project employment, with potential to be prolonged.
Application process
The application is to be submitted on the NetRecruiter system.
Karolinska Institutet är ett av världens ledande medicinska universitet. I Sverige står Karolinska Institutet för drygt 40 procent av den medicinska akademiska forskningen och har det största utbudet av medicinska utbildningar. Sedan 1901 utser Nobelförsamlingen vid Karolinska Institutet mottagare av Nobelpriset i fysiologi eller medicin.
Enligt Riksarkivets föreskrifter arkiveras ansökningshandlingar i två år efter att tillsättningsbeslutet vunnit laga kraft. Detta gäller dock ej bilagor som är tryckta eller på annat sätt publicerade.
Karolinska Institutet strävar efter att vara en arbetsplats med jämn könsfördelning som är fri från diskriminering och ger lika möjligheter för alla.
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Publiceringsdatum2012-11-06Arbetstider och omfattning100 % visstidsanställning till 2014-12-31
Så ansöker duSista dag att ansöka är 2012-11-30
Ange följande referens när du ansöker: 6612/2012
Ansökan kan tyvärr inte göras via e-post.
Klicka på denna länk för att göra din ansökanKontaktTeam Leader Martin Scobie, +46 8 524 81558
Research Manager Kristina Edfeldt, +46 8 524 81569
Facklig kontaktAnna Aleman, OFR, 08-524 866 07
Biborka Bereczky Veress, SACO, 46 70-173 85 75
Gunnar Stenberg, SEKO, 08-524 880 75
FöretagKarolinska Institutet, Institutionen för medicinsk biokemi och biofysik
AdressKarolinska Institutet, Institutionen för medicinsk biokemi och biofysik
Karolinska Institutet
17177 Stockholm
Jobbnummer 1384300
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