Senior Research Scientist - Protein Therapeutics
AstraZeneca AB / Apotekarjobb / Södertälje
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hela Sverige AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
The arena
Within our Global DMPK Department, the section Screening and Profiling (S&P) In Vivo Large Molecule is responsible for delivery of quality in vivo DMPK data to support large molecule projects within the CNS&Pain and CVGI portfolios from target selection up to Dose Range Finding safety.
The role
Accountable for the timely delivery of DMPK in vivo data to support iMeds/GMD projects, including in vivo formulation support, in life dosing? and PK bio analysis, non-compartmental PK data-processing and reporting of exposure in preclinical (side)effect studies. Responsible for design, conduct, interpretation and reporting of routine and on occasion non-routine DMPK studies. Works independently to contribute to the design and analysis of experimental procedures by incorporating the views of others. Effectively communicate results, plans and strategies via scientific reports, oral and written methods of communication. Participate in and contribute to local discipline review groups.
Minimum experience
B.Sc.or equivalent degree in a relevant discipline.
Several years of hands-on experience using ELISA, Gyros, Mesoscale, Biacore and related platforms for quantitative analysis of large molecule drugs and immunogenicity testing. Experience in setting up of methods using these techniques.
Experience in basic pharmacokinetic data-analysis using WinNonlin or equivalent and reasonable understanding of the PK/PD principle.
Understanding of the impact of immunogenicity in preclinical pharmacology studies.
Understanding of the discovery and development process for protein therapeutics.
Track record of delivering in discovery and/or development setting.
Strong leadership capabilities with emphasis on DMPK scientific excellence.
Strong oral and written communication skills in English and oral communication in Swedish.
Preferred experience/requirements
Experience of biotherapeutic drug discovery and development process and familiarity with regulatory principles and guidelines. A flexible team player.
More information
For more information about the position please contact: Annette Persson at +46 8 553 27507.
You are welcome with your application via
http://astrazeneca.se/Career/Vacancies?itemId=10569089 Ref. SOD00000162 no later than May 15, 2011.
Publiceringsdatum2011-04-29Arbetstider och omfattningTillsvidare
Heltid
ErsättningFast lön
Så ansöker duSista dag att ansöka är 2011-05-15
Welcome with your application via Ansökan sker via företagets webbplats.
Ange följande referens när du ansöker: SOD00000162
Ansökan kan tyvärr inte göras via e-post.
FöretagAstraZeneca AB
AdressAstraZeneca AB
15185 Södertälje
KontaktuppgifterTelefonnummer: 08-553 260 00
Jobbnummer 917672
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