Scientist Bioinformatics
Dfind Science & Engineering AB / Apotekarjobb / Göteborg
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We are now looking for a Scientist Bioinformatics for an assignment at AstraZeneca
CVMD Innovative Medicines (CVMD iMed) within AZ is accountable for the discovery and the development of new drugs in the cardiovascular and metabolic arena up to Ph2 within three main strategic areas - cardiovascular/heart failure, diabetes (insulin resistance and islets health), chronic kidney diseases and NASH. Translational Sciences (TS) Department in CVMD iMed has the remit to bridge pre-clinical, early and late drug development by providing early target validation in human and by driving precision medicine approaches through biomarker science.
Main Duties and Responsibilities
As a Scientist, Bioinformatics in the Translational Science (TS) Bioinformatics group you will play a key role in supporting pre-clinical and early clinical projects or patient studies to drive human target validation, experimental models evaluation and biomarkers discovery. In this role, you will
• play a key role in advancing the team's bioinformatics and systems biology strategy focused on heart failure (HF), type 2 diabetes (T2D), chronic kidney disease(CKD) and nonalcoholic steatohepatitis (NASH).
• identify relevant human-centric 'omics' datasets and analyze them to create novel hypothesis for target identification and prioritization. Dataset for analysis will be public and proprietary, and will include transcriptomic (microarray and RNA-seq), proteomic, interactomic and metabolomics.
• You will be also responsible for integration of multivariate data from different modalities (including clinical phenotypes and biomarkers when available).
• benchmark and deploy existing bioinformatics approaches/pipelines, and develop novel computational approaches.
• be responsible to find new ways of interpreting, modelling or finding meaningful patterns in complex data.
• have the opportunity to contribute to the ongoing development of CVMD human target validation strategy.
• foster a culture of scientific excellence through regular publication of your work in peer reviewed journals, and participation in scientific forums.
Essential Requirements
• Master degree in one of the following disciplines - life science, bioinformatics, genetics/genomics, computational biology, systems biology
• Hands on experience in analyzing data generated using one or more platforms e.g. expression arrays, proteomics, lipidomics and/or next generation sequencing technologies.
• Experience in pathway and network analysis approaches to generate biological hypothesis.
• Experience in working with bioinformatics portals/databases such as UCSC Genome Browser, NCBI Entrez, dbSNP etc.
• Good programming skills in Perl/Python and high degree of familiarity with R/Bioconductor.
• Expert in using Linux command-line tools and writing shell scripts.
• Awareness of graph modeling, machine learning, Bayesian analytics or other non-traditional approaches to model biological data
• An enthusiasm to explore non-traditional approaches to bring big data together in biologically meaningful ways.
• Experience of working in collaborative projects involving cross-disciplinary and global teams.
• Skilled in effective communication of complex data to a non-expert.
Business: Dfind Science & engineering
City: Göteborg
Deadline for applications: 2017-05-26
More information:
Eleonor.ehrman@dfind.se [ mailto:
Eleonor.ehrman@dfind.se ]
Organization/Business description:
Dfind Science & Engineering är ett konsult- och rekryteringsföretag som erbjuder en omväxlande karriär som konsult inom teknik och naturvetenskap.
Hos oss har du möjlighet att utveckla dina kunskaper och bygga CV genom olika uppdrag hos våra utvecklings-, forsknings- och produktionsintensiva kunder samtidigt som du får stöd och vägledning från din konsultchef.
Vi är auktoriserade via Almega och följer deras kollektivavtal. Vi har dessutom förmåner som friskvårdsbidrag, företagshälsovård, försäkringar och rabatt på träningskort.
Välkommen till oss för en omväxlande och trygg karriär som konsult.
Varaktighet, arbetstid
Heltid Visstid
Publiceringsdatum2017-05-16ErsättningFast lön
Så ansöker duSista dag att ansöka är 2017-05-26
Ange följande referens när du ansöker: 201053903
Klicka på denna länk för att göra din ansökanKontaktEleonor Ehrman
eleonor.ehrman@dfind.seFöretagDfind Science & Engineering AB
AdressDfind Science & Engineering AB
Östra Hamngatan 23
41110 GÖTEBORG
KontorsadressÖstra Hamngatan 23, 41110 GÖTEBORG
Jobbnummer 3503286
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