Post Doctoral Opportunity in Drug Safety and Metabolism and RIA

AstraZeneca Göteborg / Apotekarjobb / Mölndal
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Post Doctoral Opportunity in Drug Safety and Metabolism and Respiratory & Inflammation (RIA), Gothenburg, Sweden.

Immunomodulatory drugs confer altered host defence immune responses in the diseased lung.

We're currently looking for talented scientists to join our innovative academic-style Postdoc. From our centre in Gothenburg, Sweden, you'll be in a global pharmaceutical environment, contributing to live projects right from the start. You'll take part in a comprehensive training programme, including a focus on drug discovery and development, given access to our existing Postdoctoral research, and encouraged to pursue your own independent research in cutting edge laboratories. It's a newly expanding programme spanning a range of therapeutic areas across a wide range of disciplines.

What's more, you'll have the support of a leading academic advisor, who'll provide you with the guidance and knowledge you need to develop your career. This is an exciting area that hasn't been explored to its full potential, making this an opportunity to make a real difference to the future of medical science.

About AstraZeneca

AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energised and rewarded for their ideas and creativity.

Our Respiratory, Inflammation and Autoimmunity team offers definitive expertise to colleagues across the business. Here, you'll help patients in areas with medical needs that aren't being fully met, including chronic obstructive pulmonary disease, asthma and rheumatic disorders. Right now we're a leading figure in inhaled drug development, and our new Inhalation Centre in Gothenburg Sweden is set to extend that lead even further

The successful applicant will have the opportunity to work across a global team with expertise in both preclinical and clinical tissues. The candidate, with support from supervisors across our Global team, will have the accountability of establishing a novel in vitro model of pathogen interaction with the lung to study the impact of novel drug candidates on the immune processes deployed to control infection. This area of research involves collaboration across multiple AstraZeneca and MedImmune sites/departments alongside an expert academic collaborator and thus the candidate should be comfortable working across multiple teams and presenting data to various interested parties. The successful candidate will have responsibility to communicate the data and present both internally and at external scientific meetings, as well as through the preparation of manuscripts relating to the work.

As a Postdoctoral Scientist in Drug Safety and Metabolism you will be:

• Utilising human and murine lung tissue slices and focus on identifying signalling pathways regulating host-pathogen interactions and effects of immunomodulatory mechanisms on these pathways.
• Defining the effect of immunomodulatory agents on signalling regulating anti-microbial responses.
• Translating the in vitro observations into a humanised mouse model.

Minimum Requirements, Education and Experience:

Essential:

• PhD in Biological Science, with a good understanding in immune cell biology
• Proven record of work published in reputable scientific journals
• Experience of setting up in vitro and/or in vivo studies involving either respiratory viruses or bacteria
• Excellent communication skills and ability to work across multiple teams

Desirable:

• Experience of immunoassays, immunohistochemistry and molecular biology techniques
• Experience in handling and culturing of human tissue derived primary cells
• Confocal imaging and data analysis expertise
• Experience with generating "omics" type data, ex. RNAseq and analysing large data sets

AstraZeneca welcomes applications from all sections of the community.

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

This is a 2 year Fixed Term Contract opportunity with a competitive salary on offer. If you require further information about this role, please contact Kinga.balogh@astrazeneca.com

More than ever, science is accelerating our rate of understanding in a wide range of medical fields - and that's only set to increase. As a global, science-led biopharmaceutical business, AstraZeneca is at the forefront of that evolution. That means an unparalleled product portfolio and a strong pipeline across all stages of the drug development process. Everything we do comes back to improving the health of our patients worldwide, and to make that happen we're focusing on some of the most challenging diseases facing humanity today.

We have a highly collaborative culture, where you'll be encouraged to push the boundaries of science while developing industry-recognised skills and experiences.

Publiceringsdatum
2017-01-27

Så ansöker du
Sista dag att ansöka är 2017-02-27
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Företag
AstraZeneca Göteborg

Adress
AstraZeneca Göteborg
Pepparedsleden 1
43183 MÖLNDAL

Kontorsadress
Pepparedsleden 1

Jobbnummer
3285697

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