Post Doc- Chromatography Modeling

GE Healthcare Bio-Sciences AB / Kemiingenjörsjobb / Uppsala
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"mAb applications" is a section within the Downstream Resins Department (~100 people) which belong to the Global BioProcess R&D (~500 people). The section is based in Uppsala and consists of ~15 highly skilled research engineers and scientists all with a solid background in molecular biology, bioanalysis and downstream purification.

Essential Responsibilities:
The section is responsible for designing downstream processes for monoclonal antibodies and related molecules and is also contributing to the development of new resins based on structure function relationships. Statistical modelling together with deep chromatographic understanding are two cornerstones in our daily work.
We are now looking for an experienced person that can contribute to our development of multimodal ligands. We are seeking a chromatography modeling Post Doc to join our entrepreneurial team for development of an iterative approach to explorative ligand selectivity maturation.
Generation of descriptive chromatographic data and mechanistic modeling applied to directed ligand libraries will be combined with ligand structure and protein descriptors to accelerate the development of new purification solutions addressing the increased challenges facing biopharma due to increased molecular diversity in the pipeline.
The Post-Doctoral Program takes the innovative research proposals of GE Life Sciences teams and places the research, development, and delivery of these inventions in the hands of our Post-Doctoral Investigators and the cross-functional teams working with them.
We are looking for someone with entrepreneurial spirit to join the leagues of innovative thinkers driving the development of world-changing technology, taking responsibility for the experimental part as well as the mechanistic modelling of downstream unit operations.

This is a temporary position of 12 months. Please apply no later than 15 January 2020.
For questions, please contact hiring manager Eva Heldin: tel. +46 (0)18 612 0391 or eva.heldin@ge.com.

Candidates should note that this role will be in scope for the proposed transition of GE Biopharma to Danaher and will transfer to Danaher at close of this transaction.

Qualifications/Requirements:
Ph D with focus on modelling of preparative chromatographic separations or equivalent knowledge or experience
Experience from modelling software e.g. ChromX or CADET
Basic programming e.g. Phyton and Mathlab
Experience of performing independent research or development activities
Proven ability to plan, execute and model chromatographic experiments
Good communication skills (both written and spoken), including presentation skills
Team player and ability to work well in a multidisciplinary environment
Fluent in English and/or Swedish, both verbally and in writing
Entrepreneurial spirit

Desired Characteristics:
Experience in Quantitative Structure Property Relationship modeling including ligand structure and potentially protein structure descriptors
Experience from Design of Experiment (DoE) tools

Publiceringsdatum
2019-12-19

Så ansöker du
Sista dag att ansöka är 2020-01-12
Klicka på denna länk för att göra din ansökan

Adress
GE Healthcare Bio-Sciences AB
Björkgatan 30
75184 Uppsala

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
GE Healthcare Bio-Sciences AB (org.nr 556108-1919)
Björkgatan 30 (visa karta)
751 84  UPPSALA

Jobbnummer
5012775

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