Astra Zeneca is looking for a Senior Research Scientist
Experis AB / Övriga jobb / Göteborg
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hela Sverige AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity
The arena
Discovery Science is a global function within Innovative Medicines, IM, in AstraZeneca. Discovery Science supports innovative medicine project teams from multifunctional capability centers in Alderley Park, Boston and Mölndal. Discovery Sciences is mainly involved in early lead generation through the late Lead Optimization stage of drug discovery. It is composed of several capabilities where Reagent and Assay Development (RAD) is one among several others such as Screening Sciences and Structure & Biophysics. This position will be placed in the RAD Department where we focus on delivering different types of reagents and assays for high impact into the drug development.
The role
To provide strong expertise in the competency of Cellular Assay Development and with a strong focus on imaging-based cellular assays. To devise, champion and develop scientific areas, aligned with project needs. To be lab-focused and make significant contributions to the practical delivery of project goals through proposal and execution of experimental strategies and troubleshooting of problems.
It is essential to have good social and communication skills and to be a strong team player. Candidates should be able to work independently, take own initiatives and have a positive, goal oriented and problem solving attitude. Good organisational skills are required and you should be comfortable in presenting your results. Excellent English is required, both spoken and in writing.
Tasks
* To develop imaging-based cellular assays for target identification, target validation and phenotypic assay development
* To use qualitative and quantitative image-based cellular assays and analysis methods for drug screening, cell profiling/QC and protein expression/functionality in a biologically and statistically relevant manner
The following skills are highly desirable
* Ability to develop imaging assays for predefined endpoints and/or investigate assay space to determine optimum endpoint for projects
* In depth knowledge of one or more imaging platforms (CellInsight, Image Express, CV7000) which can be used to generate multiparameter cellular data
* Experience using Columbus image analysis software
* Culturing and functional characterization of recombinant cell lines, primary cells and iPSC
* Expertise in cell-based assay design including knowledge of detection technologies, including spectroscopic (e.g. absorbance, fluorescence modalities), luminescent, label-free detection and imaging
* Practical understanding of assay development and optimisation, including statistical tools such as factorial experimental design, to enable generation of robust, reproducible and sensitive assays
Accountabilities
* To use judgment and knowledge where appropriate to influence the work of the project, team, section and department
* To work independently to contribute to the design and analysis of experimental procedures by incorporating the views of others
* To interpret experimental data and play a significant role in the planning of further experiments
* To identify and solve problems associated with their experiments
* To schedule agreed work-plans over agreed timelines such that the objectives of the team are met
Minimum experience
You should have a Ph. D. degree or corresponding experience in a relevant scientific discipline with extensive experience in drug discovery.
Please apply by sending your CV and application as soon as possible. We select applicants continuously. If you have any questions regarding the position please contact Linda Holmberg at . Welcome with your application!
Varaktighet, arbetstid
Heltid Contract
Publiceringsdatum2016-12-27ErsättningEj angivet
Så ansöker duSista dag att ansöka är 2017-01-03
Ange följande referens när du ansöker: 15202
Klicka på denna länk för att göra din ansökanKontaktLinda Holmberg
lindah@manpower.seFöretagExperis AB
AdressExperis AB
41104
41104 1480
KontorsadressLilla Bommen 5
Jobbnummer 3234378
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