Statistical Science Director

AstraZeneca / Biomedicinjobb / Göteborg
2018-10-29
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Statistical Science Director

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We are currently seeking an experienced Statistician to join AstraZeneca Cardiovascular, Diabetes and Metabolic function, either at the level of Principal Statistician, or at Statistical Science Lead.

As a Statistician in Biometrics & Information Sciences (B&I) - the home of late stage biometrics at AstraZeneca - you will build on your existing experience and knowledge in CVRM (Cardio Vascular, Renal Medicine & Metabolic Disease) statistics to play a crucial role delivering one of the most exciting drug portfolios in the industry. Our Therapeutic Area aligned Statistics groups oversee and deliver the statistical contribution to design, decision-making, interpretations and communication of the Therapeutic Area portfolio and is engaged in shaping the external environment.

Location can be in Gothenburg - Sweden, Cambridge UK or Gaithersburg - US.

As Statistical Science Lead you will lead the statistical contribution and statistical design of drug project teams on projects transitioning into late phase development, products in Phase III development or in Established Brand teams in lifecycle development. You will play a key role formulating the go/no decisions at the end of Phase II, in planning the product development, strategies, ensuring effective design and delivery of studies and submissions, interpretation and communication of results, in strong collaboration with external partners and support value demonstration and commercialisation of the product including Health Technology Assessment (HTA), and global publication team activities. Our Statistical Science Leads provide highly experienced strategic input, statistical expertise, and leadership to project teams in the design and interpretation of clinical studies and programmes of studies.

Main Duties & Responsibilities:

* To lead the strategic, statistical thinking and contributions to the Development Plans, Regulatory Strategy, Health Technology Assessment and Commercial Presentation of AZ products.
* Leadership to statistical staff on the product world-wide so that all work is carried out with regards to AZ standards and external regulations
* Through partnership with experts, developing design options and providing high quality decision support to enable the business to make informed decisions
* Quantifying the benefit, risk, value and uncertainty of the emerging product profile.
* Setting the standards (and enforcing compliance) for statistical work within the product;
* Holding CRO/Partners accountable for the high quality standards of their deliverables;
* Represents AZ and Statistics to Health Authorities and Reimbursement/Payer Organizations for specific projects/indications;
* Promote, investigate, develop and implement novel statistical approaches, for relevant statistical issues and/or regulatory guidance and/or value demonstration.
* Develop relationships with international opinion leaders, consultants and collaborative groups.

Essential Requirements:

* MSc/PhD in Statistics or Mathematics (containing a substantial statistical component) with experience in pharma/healthcare or other relevant area
* Proven and in depth experience in pharma/healthcare or other relevant area.
* In depth knowledge of general and therapeutic area statistical methodology and regulatory requirements related to the role (Cardiovascular, Renal Medicine and Metabolic disease TA knowledge is preferred).
* Extensive experience of Development, programme design and data analysis and interpretation.
* Substantial experience of regulatory interactions and/or submissions.
* Strong Leadership experience.

Next Steps - Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience no later than November 29th. If you know someone who would be a great fit, please share this posting with them.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, gender or gender orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2018-10-29

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2018-11-17
Ange följande referens när du ansöker: R-024492
Klicka på denna länk för att göra din ansökan

Kontakt
AstraZeneca sara.jagevall@astrazeneca.com

Företag
AstraZeneca

Adress
AstraZeneca
43183
43183 1480

Kontorsadress
Pepparedsleden 1

Jobbnummer
4429110

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