Scientist/Senior Scientist NGS
Alten Sverige AB / Sjukhusteknikerjobb / Göteborg
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hela Sverige ALTEN Pharma is looking for a Scientist/Senior Scientist NGS for a consultancy assignment at AstraZeneca in Gothenburg.
At AstraZeneca, innovation is more than just research. As one of the world's leading pharmaceutical companies, we're focused on providing medicines that make a real difference in patient care. AstraZeneca R&D Gothenburg is a great place to work where you can help us continue to lead the industry in research and development. It has an entrepreneurial and collaborative culture, where you'll feel valued, energised and rewarded for your ideas and contributions. It is a place where talented people can immerse themselves in their work and make significant contributions towards scientific excellence.
You will join the Discovery Sciences organization, working within a vibrant scientific environment to support drug discovery. The Discovery Biology department of Discovery Sciences, is responsible for the generation of novel reagents and assays to support projects in the IMED (Innovative Medicines and Early development) in all phases of the drug discovery pipeline, from target discovery all the way to clinical candidate. The IMED focuses on scientific advances in small molecules, oligonucleotides and other emerging technologies and drug discovery platforms across our different core areas.
As a Scientist in the NGS team in Discovery Biology you will be contributing experimentally and intellectually to drug discovery projects in the IMED, with a focus on Cardiovascular, Renal and Metabolic (CVRM) and Respiratory, Inflammation and Autoimmunity (RIA) projects and the development of the Next-generation sequencing (NGS) discipline. This is an exciting opportunity for a talented and motivated individual to join the group in a lab-based role. The successful individual will be a key member of the team, contributing to and leading NGS activities for a diverse range of projects across several disease areas and AstraZeneca sites globally.
MAIN DUTIES AND RESPONSIBILITIES:
• To deliver according to plans over agreed timelines such that the objectives of the project are met, including delivery of more than one agreed area of work in parallel where appropriate.
• To be an effective member of Drug Discovery Project Teams, contributing novel ideas and using judgment and knowledge where appropriate to influence the work of the project.
• To work in partnership with colleagues in Discovery Sciences and across therapy areas and sites to ensure the delivery of high quality sequencing data to projects.
• To maintain an awareness of current developments in the literature and contribute to the continuous improvement process by identifying opportunities in the workplace where improvements can be made.
• Proposing experimental strategies, troubleshooting and contributing to the practical delivery of NGS projects.
Extensive hands on NGS experimental techniques including:
• RNA preparation.
• DNA isolation and fragmentation.
• Fragment analysis and nucleic acid Q.C.
• Library preparation of various protocols.
• Operation of NGS instrumentation.
• Processing, handling and movement of large sets of data.
• Using Automation to process samples for NGS library preparation.
• Significant molecular biology skills, including PCR, analysis and Q.C.
ESSENTIAL REQUIREMENTS
• BSc/MSc degree with significant relevant experience, preferably in the pharmaceutical or biotechnology industry.
• Experience of operating NGS instrumentation, ideally Illumina platform.
• Experience of practical work for various NGS library preparation methods. For example, RNA-seq and Amplicon-seq.
• Good problem solving skills, good scientific judgement and communication skills.
• Excellent team working and networking skills with experience of interacting effectively across teams.
DESIRABLE REQUIREMENTS
• A practical understanding of a wide range of methods and technologies as applied to cellular engineering. For example, mammalian cell growth, Precise genome editing.
• Measuring off-target effects of precise genome edited cells.
ABOUT ALTEN
For over 20 years, ALTEN has developed its business by keeping to the core values ??that have built up the company's success. Every year, hundreds of ALTEN consultants have been given the opportunity to embark on challenging technical projects for our customers. ALTEN has a tradition of developing products in many areas, and history in Sweden is based primarily on skills in mechanics, software and electronics. Thanks to a successful concept in which we utilize the expertise of experienced consultants and develop young abilities towards a successful career, we have gained ground in many industries. Our Pharma initiative is based on the same successful concept with the same strong structure, but in a new exciting industry and a new field of expertise that includes knowledge in chemistry, biotechnology and biomedicine.
As an employee at ALTEN, we offer you a competitive salary based on your performance and work experience. You also have the opportunity to influence your assignments, different benefits and your overall working environment as well as choose your career path. We offer a wide range of internal trainings and an opportunity to plan for an international career. It is our conviction that genuine commitment is created through choice and the ability to influence your own personal development - our business model provides that opportunity. This freedom of choice enables us to offer our clients the most committed consultants, regardless of assignments. At ALTEN, we believe in growing together!
For questions about the position, please contact Rickard Westergren, Business Manager Pharma, at
rickard.westergren@alten.se.
Varaktighet, arbetstid
Heltid Tillsvidareanställning
Publiceringsdatum2018-02-20ErsättningEnligt överenskommelse
Så ansöker duSista dag att ansöka är 2018-02-26
Klicka på denna länk för att göra din ansökanKontaktHR-avdelningen, Alten
FöretagAlten Sverige AB
AdressAlten Sverige AB
Theres Svenssons gata 15
41755 Göteborg
KontorsadressTheres Svenssons gata 15, Göteborg
Jobbnummer 3977365
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