Scientist - Sample preparation and protein mass spectrometry

AstraZeneca AB / Laborantjobb / Göteborg
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Are you a dedicated Scientist who is passionate about experimental work, scientific excellence, and innovation? Do you want to be part of a team committed to providing quality data to drive chemistry optimization in drug discovery projects? Then this might be your next challenge!


We are looking for a passionate Research Scientist to join us in the Assays, Profiling & Cell Sciences department within the Discovery Sciences organization in Gothenburg, Sweden. Our focus is to provide quality data to drive chemistry optimization in drug discovery projects. Leading from the bench, you will combine good communication and team-working skills with a passion for experimental work, scientific excellence, delivery and innovation.

You will be encouraged and supported to think creatively in our dynamic environment. Here, we are free from fear of failure, free to ask the right questions and make bold decisions.

What you will do:
This is a lab-based role focused on supporting our drug discovery projects with quantitative measurements of intracellular protein levels and their turnover using high resolution mass spectrometry to understand response to treatment. The work includes independent troubleshooting and timely reporting of data according to agreed timelines. All work is conducted in close dialog with project teams, specifically in support of the Cardiovascular, Renal and Metabolism as well as Respiratory and Immunology disease area organizations locally in Gothenburg.

Essential Requirements:

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MSc or PhD within a relevant scientific discipline or demonstrated relevant experience in the Life Science industry
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Hands-on experience of working with and trouble-shooting high-resolution protein mass spectrometry equipment
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Practical knowledge of targeted or global proteomics analysis
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Excellent communication skills and an ability to operate effectively in multi-disciplinary research environment
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Independent analysis and evaluation of complex data and delivery of data to agreed timelines
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First-rate decision-making skills, coupled with tenacity to see decisions through, even in situations of ambiguity



Desirable for the role:

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Experience in protein sample preparation from cell lysates and tissues and a thorough understanding of available approaches for enrichment
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Experience with proteomics data analysis approaches
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Experience in protein turnover measurements using the SILAC approach
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Practical knowledge of design, development and validation of cellular assays for compound profiling
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Experience in the area of cell biology, in vitro pharmacology and protein homeostasis



Why AstraZeneca?
At AstraZeneca, we follow the science to explore and innovate. We are committed to treating, preventing, modifying and even curing some of the world's most complex diseases. Our team is driven by our desire to understand and reveal new insights. We are always learning from those living with diseases and harnessing digital, data science & AI to fast-forward our research. Join us as we push the boundaries of science to deliver life-changing medicines.



So, what's next? If this sounds like your next challenge - please apply today!

We look forward to your application, but no later than October 15, 2024.

For more information about the position please contact hiring manager Linda Sundström at linda.sundstrom@astrazeneca.com.


Additional information
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2024-10-04
Klicka på denna länk för att göra din ansökan

Arbetsgivarens referens
Arbetsgivarens referens för detta jobb är "R-209526".

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Astrazeneca AB (org.nr 556011-7482)

Arbetsplats
AstraZeneca

Kontakt
AstraZeneca
karin.tomin@astrazeneca.com

Jobbnummer
8917137

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