Pharmacometrician/Sr Pharmacometrician
AstraZeneca Mölndal / Apotekarjobb / Mölndal
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hela Sverige AstraZeneca is one of the world's leading pharmaceutical companies, with strong positions in many therapeutic areas of the global pharmaceutical market. AstraZeneca's Research & Development is based in a number of centres of excellence with state of the art facilities in Sweden, United Kingdom and North America. AstraZeneca has a world-class record of innovative, important prescription medicines for the treatment of gastrointestinal, cardiovascular, and respiratory diseases, cancer, diseases of the central nervous system, as well as treatment of pain.
The role
This is a scientific role within our Clinical Science group which is involved in candidate drug (CD) selection and in all clinical phases of the product development including registration and commercialization. We are looking for several individuals to fill the roles of Pharmacometrician or Sr. Pharmacometrician in Sweden.
In the implementation of Model Based Drug Development (MBDD), the Pharmacometrician (PM) and Sr. PM will work closely together with other modeling skills (such as preclinical PKPD scientists, statistical modelers etc) to develop MBDD plans for disease area related as well as compound related modeling. The PM and Sr. PM will develop pharmacostatistical models including disease models, exposure response models, biomarker - efficacy models etc. The PM/Sr. PM works as a partner in multi-disciplinary development teams by providing MBDD expertise. Effective collaborations with physicians, DMPK PK/PD scientists, statisticians, clinical pharmacologists and regulatory affairs experts are of key importance.
The Sr. Pharmacometrician will, together with statisticians, have the overall accountability for the MBDD plan. We will also look to these individuals to collaborate externally by publishing their work, building relationships with academic institutions and building their expertise by networking with individuals in the pharmacometric field. Individuals in the senior role will also be called upon to coach less senior staff in their modeling work.
Minimum experience
For the Pharmacometrician role, candidates will have a doctorate degree (preferred) but a Master's degree and other relevant academic training is acceptable. Candidates should have demonstrated expertise in pharmacometrics and strong quantitative skills (e.g. experience in mechanistic modeling/systems pharmacology, quantitative translational scaling, literature meta-analyses, population modeling). The PM's experience may have been gained in a variety disciplines including pharmacology, pharmaceutical sciences, biostatistics, medicine, mathematics, physiology, or engineering.
For the Sr. Pharmacometrician role, a doctorate degree with demonstrated expertise in pharmacometrics and strong quantitative skills (e.g. experience in mechanistic modeling/systems pharmacology, quantitative translational scaling, literature meta-analyses, population modeling) is required. The Sr. PM's experience (>5 years) may have been gained in a variety disciplines including pharmacology, pharmaceutical sciences, biostatistics, medicine, mathematics, physiology, or engineering. At least 5 years of his/her experience should have been gained by working in drug development in the pharmaceutical industry.
More information
For more information please contact Marie Sandström at +46 8 553 278 35, or Per-Henrik Zingmark at +46 8 553 239 42.
Welcome with your application no later than December 13, 2011.
Publiceringsdatum2011-11-29Arbetstider och omfattningTillsvidare
Heltid
ErsättningFast lön
Så ansöker duSista dag att ansöka är 2011-12-13
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Klicka på denna länk för att göra din ansökanAnge följande referens när du ansöker: SWE000000NT
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FöretagAstraZeneca Mölndal
AdressAstraZeneca Mölndal
43183 MÖLNDAL
KontaktuppgifterTelefonnummer: 031-7761000
Jobbnummer 1093011
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