Bioanalysis Scientist Dmpk
Poolia Göteborg AB / Biologjobb / Göteborg
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hela Sverige We are now looking for a talented Bioanalysis Scientist at AstraZeneca Gothenburg for a 12-months consulting assignment starting as in March. The team you will be part of is focusing on metabolism, biodistribution and disposition of small molecule, conjugated peptide and nucleotide drug candidates. You will have the opportunity to contribute to the discovery of new life changing medicines for patients and demonstrate and witness what science can do. If you are interested, apply today!
About the consulting assignment
The arena:
Cardiovascular, Renal and Metabolism (CVRM) is one of the three main therapeutic
research area within Innovative Medicines and Early Development (IMED) which deliver
candidate drugs into late-stage clinical development. CVRM is based in AstraZeneca's
world-class vibrant R&D center, located in Gothenburg, Sweden. CVRM DMPK interacts
with other functions in supporting CVRM projects all along the value chain, from target
selection all the way to market launch and Life cycle management. Now we are looking for a bioanalytical scientist with in depth knowledge in the area of quantitative bioanalysis of drugs and drug metabolites to join our team in the CVRM DMPK
department for a consultant assignment. The team you will be part of is focusing on
metabolism, biodistribution and disposition of small molecule, conjugated peptide and
nucleotide drug candidates. You will have the opportunity to contribute to the discovery of new life changing medicines for patients and demonstrate and witness what science can do.
Tasks and responsibilities:
You will be responsible for analysing drug candidates and their metabolites in various in
vitro and in vivo samples including plasma, tissue, and bile samples as well as sub-cellular
fractions. Your responsibility will include delivering quality in vitro and in vivo bioanalytical data including analysis of drugs, drug candidates and drug metabolites in various in vitro and in vivo samples to support PKPD (Pharmacokinetics and Pharmacodynamics) and biotransformation work in projects from target selection to LCM (life cycle management). The data generated is mainly aimed to provide insight to quantitative pharmacology as well as to right tissue and right exposure aspects, including the fates of drugs and their metabolites. This laboratory based scientific role includes developing and validating methods to enable delivery of data with the necessary quality and scientific information aligned with the project needs. The role requires interactive, effective communication to provide clear data and guidance to project representatives, act as an example to other scientists, and contribute to the overall team delivery. It will require making judgements about bioanalysis information, developing innovative solutions and applying cross-disciplinary understanding.
About you
Minimum requirements and key factors:
• M.Sc or equivalent degree in a relevant discipline is required
• Track record of delivering state-of-the-art bioanalysis data to projects in discovery
and/or development setting
• Good knowledge of liquid chromatography and mass spectrometry ionization and
detection (LC-MS/MS) and bioanalytical work in Drug Discovery & Development
• Basic understanding of DMPK
• Understanding of the overall drug discovery and development process
• Good communication skills in English, both verbal and in writing are required
• Demonstrated ability to work in team and independently
About AstraZeneca
AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
Warmly welcome to Poolia Life Science and AstraZeneca Gothenburg!
Varaktighet, arbetstid
Heltid Sex månader eller mera
Publiceringsdatum2019-01-23ErsättningFast månads- vecko- eller timlön
Så ansöker duSista dag att ansöka är 2019-01-29
Ange följande referens när du ansöker: 52504
Klicka på denna länk för att göra din ansökanFöretagPoolia Göteborg AB
AdressPoolia Göteborg AB
Kungsgatan 42
41115 Göteborg
KontorsadressKungsgatan 42
Jobbnummer 4573154
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