Senior Research Scientist - focus on Imaging-based Assays
Dfind Science & Engineering AB / Biologjobb / Göteborg
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hela Sverige Senior research scientist Cellular Assay Development with focus on Imaging-based Assays
Senior Research Scientist
Cellular Assay Development with focus on Imaging-based Assays
We are currently looking for a Senior Research Scientist for a 7 months consultant assignment at AstraZeneca in Gothenburg
AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity
Discovery Science is a global function within Innovative Medicines, IM, in AstraZeneca. Discovery Science supports innovative medicine project teams from multifunctional capability centers in Alderley Park, Boston and Mölndal. Discovery Sciences is mainly involved in early lead generation through the late Lead Optimization stage of drug discovery. It is composed of several capabilities where Reagent and Assay Development (RAD) is one among several others such as Screening Sciences and Structure & Biophysics. This position will be placed in the RAD Department where we focus on delivering different types of reagents and assays for high impact into the drug development.
Business: Dfind Science & Engineering
City: Göteborg
Omfattning: Full time, 1st February - 31st August
Deadline for applications: 8 January 2017, however interviews will be performed on a continuous basis so please send your application as soon as possible. Applications to be written in English.
More information: Stefan Bäckström,
stefan.backstrom@dfind.se [ mailto:
stefan.backstrom@dfind.se ], 0725-382898 or Camilla Bågenholm,
camilla.bagenholm@dfind.se [ mailto:
camilla.bagenholm@dfind.se ], 0733-434777
Qualification:
The role
To provide strong expertise in the competency of Cellular Assay Development and with a strong focus on imaging-based cellular assays. To devise, champion and develop scientific areas, aligned with project needs. To be lab-focused and make significant contributions to the practical delivery of project goals through proposal and execution of experimental strategies and troubleshooting of problems.
It is essential to have good social and communication skills and to be a strong team player. Candidates should be able to work independently, take own initiatives and have a positive, goal oriented and problem solving attitude. Good organisational skills are required and you should be comfortable in presenting your results. Excellent English is required, both spoken and in writing.
Tasks
• To develop imaging-based cellular assays for target identification, target validation and phenotypic assay development
• To use qualitative and quantitative image-based cellular assays and analysis methods for drug screening, cell profiling/QC and protein expression/functionality in a biologically and statistically relevant manner
The following skills are highly desirable
• Ability to develop imaging assays for predefined endpoints and/or investigate assay space to determine optimum endpoint for projects
• In depth knowledge of one or more imaging platforms (CellInsight, Image Express, CV7000) which can be used to generate multiparameter cellular data
• Experience using Columbus image analysis software
Culturing and functional characterization of recombinant cell lines, primary cells and iPSC
• Expertise in cell-based assay design including knowledge of detection technologies, including spectroscopic (e.g. absorbance, fluorescence modalities), luminescent, label-free detection and imaging
• Practical understanding of assay development and optimisation, including statistical tools such as factorial experimental design, to enable generation of robust, reproducible and sensitive assays
Accountabilities
To use judgment and knowledge where appropriate to influence the work of the project, team, section and department
To work independently to contribute to the design and analysis of experimental procedures by incorporating the views of others
To interpret experimental data and play a significant role in the planning of further experiments
To identify and solve problems associated with their experiments
To schedule agreed work-plans over agreed timelines such that the objectives of the team are met
Minimum experience
You should have a Ph. D. degree or corresponding experience in a relevant scientific discipline with extensive experience in drug discovery.
Organization/Business description:
Dfind Science & Engineering är ett konsult- och rekryteringsföretag som erbjuder en omväxlande karriär som konsult inom teknik och naturvetenskap.
Hos oss har du möjlighet att utveckla dina kunskaper och bygga CV genom olika uppdrag hos våra utvecklings-, forsknings- och produktionsintensiva kunder samtidigt som du får stöd och vägledning från din konsultchef.
Vi är auktoriserade via Almega och följer deras kollektivavtal. Vi har dessutom förmåner som friskvårdsbidrag, företagshälsovård, försäkringar och rabatt på träningskort.
Välkommen till oss för en omväxlande och trygg karriär som konsult.
Varaktighet, arbetstid
Heltid Tillsvidare
Publiceringsdatum2016-12-27ErsättningFast lön
Så ansöker duSista dag att ansöka är 2017-01-09
Ange följande referens när du ansöker: 201014331
Klicka på denna länk för att göra din ansökanKontaktStefan Bäckström
stefan.backstrom@dfind.seFöretagDfind Science & Engineering AB
AdressDfind Science & Engineering AB
Östra Hamngatan 23
41110 GÖTEBORG
KontorsadressÖstra Hamngatan 23, 41110 GÖTEBORG
Jobbnummer 3234336
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