Sr Research Scientist
AstraZeneca Mölndal / Biologjobb / Mölndal
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AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
The arena
To develop and generate cell lines with precise genome modifications using genome editing methods and tools, aligned with project needs and discipline enhancement. To characterize modified cell lines and analyze data generated from screening studies. Lab-based role, proposing experimental strategies, troubleshooting and making a significant contribution to the practical delivery of projects in accordance with all AZ corporate responsibility policies. Provides disciplinary scientific leadership and represents the department at interdisciplinary meetings internally as well as externally. The following skills are highly desirable:
Extensive hands on Cell Line Generation experience using a variety of methods, including genome editing tools (ZFN, TALEN and CRISPR /CAS)
Experience culturing different mammalian cell types including iPS and primary cells.
Solid understanding and practical experience of Assay Development and Screening.
Strong molecular biology skills including gDNA, PCR and RNA isolation and molecular cloning skills
Experience with virus generation (lentivirus, AAV, adenovirus)
Experience with integrative 'omics analysis (transcriptomics, proteomics, metabolomics)
Innovative publications and excellent oral and written communication skills and organizational skills
The role
Accountabilities
To lead and act as a mentor, coach and role model for research scientists.
To have strong collaboration skills
To work independently to contribute to the design and analysis of experimental procedures by incorporating the views of others
To interpret experimental data and play a significant role in the planning of further experiments.
To maintain an awareness of current developments in the literature.
To be an effective team member in supporting Discovery Projects
To identify and solve problems associated with their experiments.
To achieve personal scientific visibility through project contributions, internal presentations and publications.
To conduct where appropriate in parallel more than one agreed area of work to agreed timelines.
Technical Lead/Supervisor
This role is a technical specialist in Cell Line Generation using Genome Editing. A hands-on lab-based role at the forefront of the Genome Editing technology with a focus on effective delivery, troubleshooting and putting ideas into action. Provides support, supervision and coaching to scientists, ensuring that methods run efficiently and correctly, developing and guiding the set-up of new methodologies.
Minimum experience
Ideally should have a Ph. D. degree or corresponding experience in a relevant scientific discipline with several years of relevant experience in drug discovery and/or early development or in a leading academic institution.
Functional and Business knowledge..
To read FULL JOBDESCRIPTION and to APPLY, please vist
www.astrazeneca.sePubliceringsdatum2014-06-25Arbetstider och omfattningTillsvidare
Heltid
ErsättningFast lön
Så ansöker duSista dag att ansöka är 2014-07-04
Ange följande referens när du ansöker: MOL000001AU
FöretagAstraZeneca Mölndal
AdressAstraZeneca Mölndal
43183 MÖLNDAL
KontorsadressPEPPAREDSLEDEN 1
MÖLNDAL
Övriga kontaktuppgifterTelefonnummer: 031-7761000
Jobbnummer 1921281
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