Diploma Worker, AstraZeneca, Gothenburg, 30 hp
Proffice Link AB / Kemistjobb / Mölndal
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hela Sverige Master Thesis "Explorations in separation methodologies employing supercritical fluid chromatography"
Diploma Worker, AstraZeneca, Gothenburg, 30 hp.
Title: Explorations in separation methodologies employing supercritical fluid chromatography
Background
Chromatographic methodologies are among the most used techniques in analytical measurements and employed in diverse fields such as pharmaceutical, medical, petrochemical, forensic, etc. Samples can be of natural or synthetic origin from low molecular weight to polymers in the range of millions. Although liquid chromatography has been around for decades, a continuous development in instrumentation and configuration have taking place. This includes supercritical fluid chromatography (SFC) which has gained a renewed and increasing interest within separation science, especially regarding analytical-scale separations and, again, mainly driven by instrumental improvements. Compared to liquid chromatography, fast separations with high resolution can be obtained under various conditions extending from non-polar to relatively polar.
Objective
In SFC the advancement of polar analytes are especially important in attempt to push the border for such compounds in this otherwise more "hydrophobically" oriented technique. One goal is to obtain an understanding of chromatographic conditions and how these can expand the applicability of the technique towards polar samples and possibly contribute to a compatibility to complex constituents/matrices. Where appropriate the results are to be compared with UHPLC capabilities. Another is to find generic approaches for method development within SFC.
Chromatographic parameters, e.g. type of column, mobile phase composition, additives, pressure, and temperature will be varied to examine peak performance and selectivity.
Applicant: should have a basic background in Analytical Chemistry, preferably with previous experience in liquid chromatographic separation techniques.
Supervisor: Morgan Stefansson, AstraZeneca, Mölndal
Last date to submit your application: 2017-05-21.
For questions, please contact Morgan Stefansson; E-mail:
morgan.stefansson@astrazeneca.comAstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
AstraZeneca co-operate with Dfind/Randstad regarding recruitment of Theses workers/Diploma workers.
Varaktighet, arbetstid
Heltid Visstid
Publiceringsdatum2017-05-03ErsättningFast lön
Så ansöker duSista dag att ansöka är 2017-05-21
Ange följande referens när du ansöker: 201048933
Klicka på denna länk för att göra din ansökanKontaktMorgan Stefansson
morgan.stefansson@astrazeneca.comFöretagProffice Link AB
AdressProffice Link AB
Pepparredsleden 1
43183 Mölndal
KontorsadressPepparredsleden 1, 43183 Mölndal
Jobbnummer 3474198
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