Team Leader - Director, New Modalities Medicinal Chemistry
AstraZeneca AB / Kemistjobb / Göteborg
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hela Sverige AstraZeneca is committed to the development of the next generation of innovative medicines. We now seek to recruit a Director, New Modalities Medicinal Chemistry to the New Modalities Medicinal Chemistry team, which is part of the department of Medicinal Chemistry, Early Respiratory & Immunology (R&I) at AstraZeneca.
The New Modalities team works in close collaboration with Computational Chemists, Analytical Chemists, Biologists, DMPK, Safety and Pharmaceutical scientists - all joined up by the goal to discover synthetic therapeutics of the future.
This is a very exciting opportunity as it combines Medicinal Chemistry of peptides and oligonucleotides, the development of cell- and tissue targeting moieties and the development of diverse types of conjugates. This role is based at our vibrant R&D site in Gothenburg, Sweden.
What you'll do?
The Director, New Modalities Medicinal Chemistry leads a team of 10 PhDs who share a strong experience in peptides, oligonucleotides, targeting ligands and conjugation of diverse modalities. As an authority in the field of peptide and/or oligonucleotide drug discovery the successful candidate is expected to make significant contributions to early target validation and the design, optimization and delivery of drug molecules for AZ 's new modality portfolio.
In this role you will have a significant impact on multiple projects across and beyond the R&I New Modality portfolio. You will lead a multidisciplinary, highly collaborative and international team and represent the department in global scientific initiatives defining strategic direction and implementing new technologies in Medicinal Chemistry. The successful candidate will host MSc/PhD students and postdocs, work with multiple academic and industrial partners and publish/patent and regularly present at internal and external conferences.
Major Duties and Responsibilities:
• Impact on R&I 's project portfolio of synthetic New Modalities
• Co-lead drug discovery projects and collaborate in crossfunctional teams
• Generation/support of new target/project proposals
• Advise project teams and senior leaders around peptides, oligonucleotides and conjugates
• Lead, develop and mentor a team of New Modalities chemists
• Initiate and lead collaborations with external and internal partners
• Publish and present internally and externally
• Manage performance and career development of direct reports
Essential skills/experience:
• PhD in Organic Chemistry, Medicinal Chemistry, Biochemistry or Chemical Biology
• In-depth experience in design, synthesis and characterization of peptides and/or oligonucleotides
• Expertise in pharmaceutical drug discovery and development of new modalities drug candidates
• Extensive interdisciplinary knowledge of drug discovery
• Experience in modern analytical, biophysical, structural chemistry and computational techniques
• Excellent leadership and interpersonal skills
• Ability to prioritize workload and manage challenging staff situations
• Excellent written and verbal communication skills
Why AstraZeneca?
AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. The Respiratory & Immunology (R&I) unit is one of AstraZeneca 's core therapy areas focused on the discovery and development of novel treatments for respiratory and immunological diseases.
What's next?
We would be delighted to receive your application until January 31st, 2024.
For more information about the position please contact: Dr. Werngard Czechtizky, Head of Medicinal Chemistry, Research and Early Development, Respiratory & Immunology (R&I), BioPharmaceuticals R&D, AstraZeneca, Gothenburg at
Werngard.Czechtizky@astrazeneca.com.
Where can you find out more about Gothenburg?
https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html Our Gothenburg site:
https://www.astrazeneca.com/our-science/gothenburg.html Life in Gothenburg:
https://www.movetogothenburg.com/ Ersättning Not Specified
Så ansöker du Sista dag att ansöka är 2024-01-15
Klicka på denna länk för att göra din ansökan Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-187550".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Arbetsplats AstraZeneca
Kontakt AstraZeneca
karolina.zingmark@astrazeneca.com Jobbnummer 8344484
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