Translational Science Lead, Imed Ria Sweden
AstraZeneca / Biologjobb / Göteborg
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hela Sverige Are you a precision medicine expert hungry for implementing new ideas, innovative ways of working and continuous learning? Do you want to join a team with excellent scientists in an environment where absolutely everyone can thrive?
The RIA Target & Translational Science (TTS) department is an agile environment, with a science and patient-focused culture. Our mission is to understand disease mechanisms at the molecular level, identify the most effective target and the right patient population and close the gap between bench science and bedside clinical practice.
As Translational Science Lead (TSL) you will have a key scientific role, developing and delivering precision medicine strategies to select the patients most like to benefit from our medicines. You will join the Precision Medicine Discovery, seeking to lead the development of precision medicine in respiratory disease, driving patient segmentation and delivering translational clinical validation.
Depending on your previous background and experience, the seniority level of the role can be adapted. We are looking forward to share this journey with you.
Main Duties and Responsibilities
In this role, you are both laboratory and project-based working with flexibility to ensure all translational aspects of the projects are supported in an effective and professional way. You will be accountable for building the translational clinical validation package for respiratory targets. To do this, you will utilise public and proprietary biobanks as well as AZ MeMo studies.
By collaborating with other co-workers, you will provide projects with the expertise needed as well as continuously strengthen the link between targets and disease phenotypes and endotypes by bringing precision medicine propositions to the clinic. Together, you will set and deliver precision medicine strategy and clinical target validation strategy.
As an authority within precision medicine, you are able to influence and utilise the external scientific community with respect to translational science and precision medicine. We expect you to share your continuously deepened mechanistic understanding of targets and their link to patients, disease and clinical outcome with colleagues, building a collaborative and constantly improving atmosphere.
Accountabilities and responsibilities
* Identification of relevant patient subgroups based on biological drivers of segmentation
* Invention, development and implementation of key patient segmentation biomarkers
* Develops target line of sight to clinic post First Time in Man
* Responsible for aligning precision medicine proposition and associated biomarker strategy with the clinical development plan
* Select relevant biomarker discovery strategies for each target toensure delivery of all translational aspects of projects through collaboration
* Stay updated with current developments in the literature and identify leading improvements in technologies
* Mentoring junior scientists to develop their skills and improve their potential
* Ensure AstraZeneca visibility by publishing papers in internationally recognized journals as well as internal and external presentations
* Aligned with relevant company policies and ensure that industry standards are applied
* Contribute to a deep understanding of own function as well as overall AZ R&D objectives
* May lead one or more aspects of the scientific discipline within their team
Essential Requirements
You possess excellent team working skills with a proven record of working collaboratively to ensure scientific excellence and robust delivery to projects. Furthermore, you are a positive person with a can-do attitude, also respecting individuals with different skillsets and knowledge.
* PhD or equivalent with a strong experimental drive and background in basic science related to respiratory research.
* Experience from pharmaceutical Research & Development and broad understanding of relevant technologies and methods along with excellent scientific laboratory skills
* Strong publication record.
* Demonstrable delivery in precision medicine and target validation
* Excellent understanding of the Respiratory therapy area and disease biology
* Experience and knowledge of the biological basis for patient segmentation, precision medicine and patient selection biomarker invention and implementation
* A good understanding of the drug development process, from lead identification through clinical development.
* Excellent communicational and interpersonal skills resulting in a broad network
Desirable Requirements
* Post-doc experience from relevant scientific field
* Approx. 10 years of work experience in pharmaceutical R&D, from lead identification through clinical trials
* Experience and solid understanding of biology, pharmacology, translational medicine and clinical sciences, with pre-eminence in at least one of these areas
If you are interested, apply now!
For more information about the position please contact Katerina Pardali,
Welcome with your application no later than January 1st, 2019.
Information about life in Gothenburg:
www.movetogothenburg.comVaraktighet, arbetstid
Heltid Permanent
Publiceringsdatum2018-12-03ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-12-31
Ange följande referens när du ansöker: R-031622
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
karin.lyckemalm@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparredsleden 1
Jobbnummer 4489028
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