Synthetic Chemist

AstraZeneca AB / Kemistjobb / Göteborg
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Would you like to apply your synthetic chemistry expertise in a global company where we work together across boundaries to make the impossible a reality?

AstraZeneca now offer an exciting opportunity for a senior scientist with great skills in synthetic organic chemistry and a special interest in bridging novel synthetic chemistry and medicinal chemistry into design and synthesis of new candidate drugs. As part of an open minded, creative and experienced team, you will contribute with your high ambitions, collaborative mindset and enthusiasm to push the boundaries of science in the area of synthetic and medicinal chemistry. The positions are placed at AstraZeneca's dynamic R&D site in Gothenburg, Sweden

Cardiovascular, Renal and Metabolism (CVRM) is one of AstraZeneca 's core therapy areas. We follow the science and turn ideas into life changing medicines for patients suffering from Heart Failure, Diabetes and Chronic Kidney Disease. We drive our pipeline and areas of scientific leadership internally and in collaborations with world experts which provides you as a scientist with the unique opportunity to access the most advanced knowledge and opportunities to stay at the fore-front of science.

The CVRM Medicinal Chemistry Department is a critical player in the discovery and design of drug molecules to identify and validate novel biological targets. We are proud of our successful delivery of clinical candidates to human testing leading to new medicines for patients. To realize our ambitions, we stay agnostic to molecular modality and we are now further expanding our team working on targeted protein degradation and PROTAC's with this position in synthetic chemistry.

Main duties and responsibilities

The role is lab based and focused in the area of medicinal chemistry with emphasis on synthetic chemistry and in particular PROTACs synthesis and design. You will actively contribute to AstraZeneca drug portfolio projects by compound design and synthesis, data generation and data interpretation. The work is done in a highly cross disciplinary environment in close collaboration with scientists from the Chemistry, Bioscience, Discovery Sciences, DMPK and Pharmaceutical Sciences departments. There will also be opportunities to develop medicinal chemistry and drug discovery knowledge together with the experts in the department. In addition, you are expected to be part of external collaborations, publish scientific papers, present and represent the department at conferences etc.

Requirements

We are looking for an ambitious team player that have expert knowledge in synthetic organic chemistry. Basic knowledge in medicinal from drug discovery in an industrial setting

* Ph. D. degree in Organic Chemistry/Synthetic Chemistry/Medicinal Chemistry or Master of Science with a few years' experience in synthetic/medicinal chemistry.
* Synthetic chemistry: ability to plan, prioritize and perform work independently including synthetic route design and problem solving
* Scientific creativity: ability to identify, develop and apply new technologies and ways of working
* Great awareness of recent literature within synthesis/medicinal chemistry as well as current developments and trends in organic synthesis
* Highly self-motivated and capable of receiving and analyzing input from complex data and deciding on focused course of action
* Excellent teamwork, collaboration, networking and communication skills
* Ability to communicate your work both to senior chemistry leaders and in scientific papers and documents

If you are interested, apply now!

For more information about the position please contact recruiting manager Dr. Daniel Pettersen,

Welcome with your application no later than December 8th, 2019.

Additional information

Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html

Life in Sweden and the wonderful city of Gothenburg: https://www.movetogothenburg.com/

Culture and atmosphere of the site: https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/



AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. Within this environment employees are empowered to express diverse perspectives, and are made to feel valued, energized and rewarded for their ideas and creativity.

AstraZeneca is acting as an Employment Agency in relation to this vacancy.

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2019-11-06

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2019-12-04
Klicka på denna länk för att göra din ansökan

Företag
Astrazeneca AB

Arbetsgivarens referens
Arbetsgivarens referens för detta jobb är "R-065317".

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Astrazeneca AB (org.nr 556011-7482)

Arbetsplats
AstraZeneca

Jobbnummer
4944165

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