Senior Scientist, In Vivo Biology
AstraZeneca / Apotekarjobb / Göteborg
2017-12-18
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hela Sverige Do you have expertise within in vivo biology that you enjoy applying in the lab? Have you worked with large and/or small animals? Would you like to apply your expertise in a company where we are following the science and turn ideas into life changing medicines? Then you might be the one we are looking for!
We are now recruiting a Senior Scientist with expertise in in vivo biology to join the heart failure in vivo team within the Cardiovascular and Metabolic Disease (CVMD) therapeutic area at AstraZeneca in Gothenburg, Sweden.
CVMD is one of the three main therapeutic research areas within Innovative Medicines and Early Development (IMED), AstraZeneca's Biotech unit that deliver candidate drugs into clinical development. AstraZeneca has a patient-centric approach for discovering novel treatments for patients with metabolic disease, chronic kidney disease and cardiovascular disease. The three areas are integrated into one unit - CVMD IMED. At the Heart failure Bioscience department we focus on identifying and validating new drug targets for patients with cardiovascular disease and heart failure. The team delivers key data to projects across all phases of the drug discovery and development and we work with different modalities such as small molecules, mRNA, antisense oligonucleotides (ASOs) and peptides.
As a Senior Scientist, In Vivo Biology you will play a key role in driving science and projects forward within the heart failure area. This role is primarily lab-based and you will explore novel drug targets and support existing projects with key in vivo and ex vivo data. Collaboration is critical for successful delivery of drug projects and you will work closely with scientists/teams from a wide range of different functions within AstraZeneca. Your in vivo work will include experimental work in large animals as well as small animals to understand pharmacokinetics and pharmacodynamics, establishing animal disease models and explore effects on cardiovascular function by different treatments in the animal models. You will perform surgical procedures when needed, establish and measure physiological parameters invasively e.g. with cardiac catheterization and non-invasively e.g. with ultrasound imaging. You will have the opportunity to try novel techniques and ideas required for progressing existing portfolio and novel science. Some in vitro work can also be part of role description.
Main Duties and Responsibilities
* Independently design, develop, execute and report in vivo studies and ex vivo assays for projects from pre-target identification to clinical stage
* Independently analyse and interpret generated data
* Maintain understanding of the science in heart failure and cardiovascular area
* Communicate data to the project teams and department
* Work collaboratively within Bioscience and other functions throughout AstraZeneca to deliver on key project activities
* Contribute to communications of scientific findings through publications in scientific journals and meetings
* Contribute proactively to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared
Essential Requirements
* Bachelor's or master's degree in Biology/Biomed analyst/Cardiovascular disease or equivalent
* Great knowledge in physiology, anatomy and experience in how to measure functional & morphological changes in vivo within the cardiovascular area
* Expert knowledge and experience in performing large and/or small animal experimental work
* Entrepreneurial and flexible ways of working
* Great collaboration skills
* Strong drive and commitment
* Strong oral and written communication skills
* Excellent English, both spoken and in writing
Desirable Requirements
* Background in drug discovery and development in the pharmaceutical industry
* PhD or equivalent academic merits in cardiovascular disease or related area
* Knowledge and experience in ultrasound imaging and/or MRI imaging
* In vitro experimental skills
If you are interested, apply now!
For more information about the position please contact Johannes Wikström at +46-31-7064526
Welcome with your application no later than January 22, 2018.
AstraZeneca is a global, innovation-driven pharmaceutical company focusing on the discovery, development and commercialization of novel medicines. At AstraZeneca, we are proud to have a unique culture that inspires innovation and collaboration both within the company and with external partners. Employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2017-12-18ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-01-15
Ange följande referens när du ansöker: R-019050
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
asa.lothigius@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparedsleden 1
Jobbnummer 3860131
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