Senior Scientist - New Modality Clinical Formulation
AstraZeneca AB / Kemistjobb / Göteborg
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hela Sverige At AstraZeneca we turn ideas into life changing medicines and strive to continuously meet the unmet needs of patients worldwide. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.
We continually push the boundaries of science to deliver medicines that treat diseases across our main therapy areas. Through our integration with Alexion, this now includes expanding the limits of scientific research to better understand rare diseases and to discover new life-changing treatments for them.
Pharmaceutical Sciences is a department within AstraZeneca Biopharmaceutical R&D. The Pharmaceutical Sciences' mission is to transform molecules into investigational medicines, meeting the unmet needs of future patients. Advanced Drug Delivery is a department in Pharmaceutical Sciences. Our portfolio of projects spans traditional small molecules, peptides oligonucleotides to RNA based therapeutics across AstraZeneca's therapy areas and our mission is to transform diverse modalities into investigational medicines.
We are now looking for a skilled and experienced Formulation Scientist to join us as Senior Scientist, in the New Modality Clinical Formulation team. The role sits within the ADD group at our vibrant R&D site in Gothenburg, Sweden. With more than 2 800 employees from over 70 different countries, our vibrant Gothenburg site is a truly inspiring place to work.
What You'll do
This is an exciting role where you will act as a key member of various project teams and provide your technical and scientific expertise into formulation design and development strategies within the new modality and advanced drug delivery portfolio of peptides, oligonucleotides and RNA based therapeutics, with emphasis on parental formulation development. You will be responsible for defining lead enabling formulations to ensure desired clinical performance from discovery to Phase II, including a strong contribution to CMC (Chemistry, Manufacturing, Control) aspects and deliveries. In addition, you will lead GxP/non-GxP drug product manufacturing and outsourcing activities and strategies. As such, we are looking for a candidate who has a strong understanding of biopharmaceutics, formulation, and drug delivery across various modalities and dosage forms. The role will be expected to work cross-functionally supporting drug projects from early to late clinical phase and be involved in science & technology initiatives.
We are looking for you, who together with your team will make a difference for patients' lives every day. This through your ability to independently lead and achieve set goals within budget, time and to the right quality.
Essential for the role
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PhD degree in relevant field (such as Chemistry, Pharmaceutics, Chemical Engineering or Biotechnology) or MSc degree with +2 years of industrial experience within the field of Pharmaceutical/Biotechnology Science.
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Hands-on experience of formulation development with biomolecules (e.g. RNA, proteins and peptides) and lipid nanoparticles for RNA delivery
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Good understanding of formulation science, drug delivery and biopharmaceutics to enable mechanistic understanding of in vivo drug product performance.
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Experience on clinical formulation development and design from the pharmaceutical industry, including knowledge of CMC deliveries and regulatory frameworks.
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Knowledge of GxP manufacturing activities and strategies, including scale-up development, outsourcing, tech transfer, reviewing and approving documentation such as Manufacturing Methods and Master Batch Records.
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Good understanding of the overall drug discovery and development process and an appreciation of how the Pharmaceutical Science field contributes to R&D.
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Ability and desire/willingness to effectively communicate, network and build collaborative relationships with partners across disciplines and cultures, internally and externally and independently lead and influence projects.
If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be. With us there are many opportunities to develop yourself and your career. From our diverse portfolio and teamwork, to our cutting-edge innovations - it's a place for lifelong learning.
Are you ready to make a difference? Send in your application, and we'll make it happen together.
For more information about the position please contact Marianna Yanez Arteta, at
marianna.yanezarteta@astrazeneca.comWe encourage you to send your application as soon as possible, but no later than 31st January.
Additional information
Our Gothenburg site
Life in Gothenburg
Ersättning Not Specified
Så ansöker du Sista dag att ansöka är 2023-02-01
Klicka på denna länk för att göra din ansökan Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-156691".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Arbetsplats AstraZeneca
Kontakt AstraZeneca
maria.elmberg1@astrazeneca.com Jobbnummer 7339896
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