Senior Scientist - Mechanistic Biology & Profiling for Discovery
Dfind Science & Engineering AB / Biologjobb / Göteborg
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hela Sverige Senior Scientist - Mechanistic Biology & Profiling for Discovery Science
The Arena
An exciting opportunity has arisen for a highly motivated Senior Scientist. This is a consultant assignment offering you to join the Mechanistic Biology & Profiling Department within the Discovery Sciences Innovative Medicine (IMED) at AstraZeneca in Gothenburg, Sweden.
Leading from the bench, you will apply proven cell biology expertise and a passion for driving scientific questions, combined with strong team working ethics, to drug discovery projects. You will join one of the Molecular Screening and Profiling teams whose remit is to support IMED projects globally with delivery of screening and mechanism of action data for project compounds.
Main Duties and Responsibilities
This is a lab-based role, providing in vitro target-based and phenotypic screening to support projects in all phases of the discovery process. The role involves proposing experimental strategies, troubleshooting and making a significant contribution to the practical delivery of projects as well as novel science to advance our capability and for external presentation.
Essential Requirements for the role
• Candidates should have a Ph.D. or a first degree and at least 4 years' experience within a relevant scientific discipline
• Expertise in cell-based screening of a variety of mammalian cell types (including primary, iPS and immortalized cell lines)
• Theoretical understanding of assay design relevant to the pharmacology of the drug target and a practical understanding of assay optimisation and use of statistical tools to enable generation of robust, reproducible and sensitive assays
• Practical knowledge of detection technologies and technology platforms compatible with cellular assays, including ideally flow cytometry and imaging
• Data analysis and conversion of screening data to biological parameters
• Experience in design and execution of complex pharmacology studies to understand compound mechanism of action
• Excellent communication skills and an ability to operate effectively in a multi-disciplinary research environment
• Independent analysis and evaluation of complex data and delivery of data to agreed timelines
• Provide technical leadership and guidance to others
• Maintain an awareness of relevant scientific and technical advances to help identify opportunities for capability development
• Scientific visibility and leadership through project contributions, internal presentations and external publications.
• Excellent problem solving skills, not limited to own area of expertise
• First rate decision making skills, coupled with tenacity to see decisions through, even in situations of ambiguity
• Track-record in publishing scientific manuscripts in peer-reviewed journals, and presenting at external conferences
• Recognized scientific expertise within the area of cell biology as applied to screening and will function as a scientific expert within project teams.
• Good understanding of drug discovery and how to translate their scientific expertise into new project and business opportunities.
Business: Dfind Science & Engineering
City: Gothenburg
Deadline for applications: 2017-09-30.
Organization/Business description:
Dfind Science & Engineering is a recruitment and consulting company within science and engineering. All our consultant managers and recruitment consultants have an education and work experience within the respective field. In combination with extensive knowledge of staff issues and solid experience of recruitment, this means that we understand our clients' need for both flexibility and the right skills.
Dfind Science & Engineering is since 2016 part of Randstad Group. With over 600 000 employees in over 40 countries Randstad is the work second largest company within recruiting and staffing.
Varaktighet, arbetstid
Heltid Visstid
Publiceringsdatum2017-09-20ErsättningFast lön
Så ansöker duSista dag att ansöka är 2017-09-30
Ange följande referens när du ansöker: 201082383
Klicka på denna länk för att göra din ansökanKontaktEleonor Ehrman
FöretagDfind Science & Engineering AB
AdressDfind Science & Engineering AB
Östra Hamngatan 23
41110 GÖTEBORG
KontorsadressÖstra Hamngatan 23, 41110 GÖTEBORG
Jobbnummer 3708144
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