Senior Research Scientist- Lung Regeneration, Imed Ria Sweden

AstraZeneca / Biologjobb / Göteborg
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Respiratory is one of AstraZeneca's main therapy areas. Our aim is to transform asthma and COPD treatment through inhaled combinations at the core of care, biologics for the unmet needs of specific patient populations, and scientific advancements in disease modification.

From a research perspective we work to understand, treat, modify and ultimately cure respiratory disease with an emphasis on four diseases with significant unmet medical need; asthma, COPD, Idiopathic Pulmonary Fibrosis (IPF) and Chronic Cough. Recently, we reshaped our strategic focus into three mechanistic and complimentary areas in chronic lung disease: Lung Immunity, Lung Epithelium and Lung Regeneration.

To further strengthen our expertise and capacity in each of these strategic research areas we are currently recruiting world-class scientists. Do you want to join our team?



Main Duties and Responsibilities

The remit of the RIA Lung Regeneration Department is to generate in vitro, in vivo and ex vivo Biology data to further our understanding of the potential in lung regeneration in chronic lung disease and support the biology ranging from the target idea stage up until Phase 3 investment decision.

We have several job openings for Senior Research Scientists in our new Lung Regeneration Department where we are looking for lab-based bioscientists able to design and develop experimental strategies that make a significant contribution to the identification of new targets, biomarkers, the progression of drug discovery projects and publishable scientific insights.



Accountabilities and responsibilities:

* Works independently designing and analysing experiments and problem solving
* Independent design, analysis and performance of in vitro and ex vivo studies, with robust interpretation and communication of data
* Be an effective team member in supporting drug discovery projects to meet their objectives
* Multi-tasking skills essential and working to agreed timelines
* Write peer-reviewed publications
* Strong influencing skills, supporting project progression and portfolio prioritisation
* Maintain an awareness of current developments in the literature
* To schedule agreed work-plans over agreed timelines to such that the objectives of their team are met
* Identify, establish and/or maintain external collaborations
* Clearly and effectively communicate their research and research from collaborations and from the literature, both in written and oral format
* Setting and adhering to personal goals and objectives
* Ensure that the work is performed with the right quality in accordance with compliance processes meeting Biology standards.
* Ensure compliance with all corporate guidelines and rules
* Will have a good working knowledge of all relevant company policies - ensure GLS compliance, compliance with corporate code of conduct and adherence to best SHE practice for self and others - and national regulations, and ensure that industry standards are applied to working for self and others within the discipline team.
* Will have a broad understanding of own function, and will have a clear understanding of overall AZ R&D objectives. Will be regarded as a source of scientific knowledge inside the department.
* Contributes to a science-driven and entrepreneurial organization hungry for new ideas, innovative ways of working and continuous learning
* Positive can-do attitude, with respect for the individuals with different skillset and knowledge, eager to learn in each interaction.
* Collaborate closely with other teams to drive efficiency and take advantage of knowledge and experiences.



Essential Requirements

* PhD, or BSc/MSc with relevant academic or industrial experience
* At least 2 years of experience in the pharmaceutical industry or equivalent qualification
* Extensive experience in fibroblast biology, mesenchymal stem cell biology and/or epithelial cell biology and relation to tissue fibrosis and regeneration research
* Experience in flow cytometric and/or flow cytometric-based cell sorting
* An understanding of respiratory diseases including COPD and IPF would be desirable
* An understanding of progression of drug targets through to the clinical setting
* Strong scientific drive, good networking and communication skills and delivery focus is required
* A good scientific publications record
* Experience in single cell RNA sequencing or transcriptomics and/or
* Experience in histopathology, IHC, in situ hybridization and image analysis and/or
* Experience with multi-cellular 3D models and/or precision cut lung slices (PCLS) of human and/or rodent lung
* A good understanding of the drug development process, from lead identification through clinical development
* Ability to work productively in a matrix team environment and excellent collaborative skills
* Excellent written and oral communicational skills
* Good networking and communication skills and a strong delivery focus



If you are interested, apply now!

For more information about the position please contact Lynne Murray,

Welcome with your application no later than August 9th, 2018.

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2018-07-06

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2018-08-03
Ange följande referens när du ansöker: R-031631
Klicka på denna länk för att göra din ansökan

Kontakt
AstraZeneca karin.lyckemalm@astrazeneca.com

Företag
AstraZeneca

Adress
AstraZeneca
43183
43183 1480

Kontorsadress
Pepparredsleden 1

Jobbnummer
4249125

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