Senior Research Scientist Organic Chemist - Discovery Sciences C
AstraZeneca Göteborg / Apotekarjobb / Mölndal
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AstraZeneca is now looking to hire a Senior Research Scientist Organic Chemist within Discovery Sciences Chemistry. Placement for the role is Gothenburg, Sweden
As a Senior Research Scientist Organic Chemist you will be part of a chemistry team focusing on the identification, exploration and implementation of new synthetic methodologies and automation technologies and their application to drug discovery. Key focus will be on high throughput experimentation and automated compound library synthesis for the purpose of accelerating internal projects from hit generation through to candidate selection. If you have effective levels of communication, scientific drive and a high interest in working with machines then you're our kind of person.
Main Duties and Responsibilities
Synthesize and purify compounds and compound libraries, covering the full spectrum of synthetic complexity and demands including compounds for biological testing, route design and development, quantities ranging from sub-milligram to gram scale.
Plan, prioritise and perform own work and actively collaborate with project teams e.g. compound library design, chemistry experiment design and application of available technology.
Drive the development and adoption of cutting-edge technologies to support the automated synthesis of new compounds.
Identify, develop and apply new, cutting-edge synthetic approaches.
Propose experimental strategies, troubleshoot laboratory based problems and make a significant contribution to the delivery of the team.
Maintain access to the best in- and external science.
Enhance business reputation internally and externally through peer-reviewed publications and oral/poster presentations.
Essential Requirements
Ph.D. in a relevant chemistry discipline with min 3 years experience in a synthetic organic chemistry and/or chemical engineering unit.
Synthetic chemist with a track record of applying innovative chemistry solutions, with resulting impact in project delivery.
Expertise in theoretical and practical organic synthesis, compound route design, purification and analytical sciences.
Hands-on experience with state-of-the-art parallel synthesis and/or high throughput experimentation technologies.
Able to prioritise and perform work independently, for example retro synthetic analysis, route design using literature, own knowledge and intergration of ideas from colleagues.
Advanced knowledge of modern chemical literature, chemical technologies and applying new ideas to project delivery.
Able to work effectively in high performing teams and demonstrated ability to work across scientific disciplines to drive results.
Able to coordinate and deliver provision of patent examples/experimental write-ups.
A track record of driving innovation in chemistry related sciences.
Understands how the different natural sciences contribute to the drug discovery process and you will be asked to represent your own area in cross-disciplinary meetings.
Thorough understanding of the chemical sciences and how they contribute and influence drug discovery together with knowledge of the drug discovery process.
Desirable Requirements
Technical understanding of functionality of lab equipment like HPLC, LCMS, flow reactor, liquid dispensing robotics.
Knowledge in designing high-throughput chemistry and/or library synthesis experiments using bespoke design software.
Experience with Design-of-Experiment (DOE) approaches and software.
Experience with microfluidics based technologies.
Mentoring/supervision of junior staff, students, etc.
For more information about the position please contact: Johan Widestrand at + 46 317761181
More than ever, science is accelerating our rate of understanding in a wide range of medical fields - and that's only set to increase. As a global, science-led biopharmaceutical business, AstraZeneca is at the forefront of that evolution. That means an unparalleled product portfolio and a strong pipeline across all stages of the drug development process. Everything we do comes back to improving the health of our patients worldwide, and to make that happen we're focusing on some of the most challenging diseases facing humanity today.
We have a highly collaborative culture, where you'll be encouraged to push the boundaries of science while developing industry-recognised skills and experiences.
Publiceringsdatum2017-03-03Så ansöker duSista dag att ansöka är 2017-03-08
Klicka på denna länk för att göra din ansökanFöretagAstraZeneca Göteborg
AdressAstraZeneca Göteborg
Pepparedsleden 1
43183 MÖLNDAL
KontorsadressPepparedsleden 1
Jobbnummer 3354875
Observera att sista ansökningsdag har passerat.