Senior Research Scientist - Synthetic Medicinal Chemistry

AstraZenecas / Logistikjobb / Göteborg
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Respiratory is one of AstraZeneca's main therapy areas. Our aim is to transform asthma and COPD treatment through inhaled combinations at the core of care, biologics for the unmet needs of specific patient populations, and scientific advancements in disease modification.

To further strengthen our expertise and capacity we are now recruiting Senior Medicinal Scientists.

AstraZeneca is one of the world's most exciting biopharmaceutical companies. From scientists to sales, lab techs to legal, we're on a mission to turn ideas into life-changing medicines that improve patients' lives and benefit society. We need great people who share our real passion for science and have the drive and determination to meet patients' needs around the world. IMED RIA 's Chemistry team is focused on driving discovery research to deliver world-class medicines with an emphasis on small to large sized synthetically accessible molecules. The team operates in a cross-disciplinary environment in close collaboration with scientists from the Chemistry, Bioscience, DMPK and Pharmaceutical Science departments to advance the RIA project pipeline.

AstraZeneca is committed to the development of the next generation of innovative respiratory medicines. In this role, you will join a highly collaborative discovery team leveraging Medicinal Chemistry to invent novel medicines.

Major Duties and Responsibilities

The position includes synthesis, purification and characterization of lead molecules from target validation to lead optimization phase, including compound design and Medicinal Chemistry aspects. You will ensure uptake of novel scientific developments into AstraZeneca 's Medicinal Chemistry project teams and influence compound design by generating ideas for novel molecules. Furthermore, this position includes the opportunity to share scientific findings and publish new scientific results.

Accountabilities and responsibilities:

* Provide state-of-the-art Synthetic Organic Chemistry to projects at all stages of drug discovery, delivering high quality drug molecules and tool compounds
* Apply synthetic chemistry with an idea generation mindset, efficiently troubleshooting problems and maintaining a clear focus on project progression
* Provide expertise in synthetic chemistry methodology, purification and analytical sciences deliver high quality compounds within agreed timelines
* Collaborate with the project chemistry team in the development, planning and prioritization of compound synthesis, route design and problem solving
* Provide quality input into compound design and MedChem optimization
* Follow safety requirements and all AZ corporate responsibility policies
* Drive RIA IMED 's scientific reputation by identifying and contributing to publication opportunities internally and externally



Essential Requirements

You are expected to have a strong scientific background in Organic Chemistry including excellent verbal and written communication skills. Furthermore, you have the ability to engage and collaborate across boundaries with a problem-solving attitude and delivery focus combined with a strong interest to develop your skills within Medicinal Chemistry.

* PhD in Synthetic Organic Chemistry, Medicinal Chemistry or Biochemistry;
* In-depth scientific knowledge of modern synthetic chemistry
* Up-to-date with the application of modern purification and analytical techniques
* A proven track record of delivery from own experimental work
* Excellent communication and teamwork skills
* Basic knowledge of the pharmaceutical drug discovery and development process preferred
* Postdoctoral and/or industrial experience preferred



If you are interested, apply now!

For more information about the position please contact Lena Ripa: Lena.

Welcome with your application no later than October 21st, 2018.



AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. The Respiratory, Inflammation & Autoimmunity (RIA) unit is one of AstraZeneca 's core therapy areas focused on the discovery and development of novel treatments for respiratory diseases.

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2018-09-21

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2018-10-19
Ange följande referens när du ansöker: R-036233
Klicka på denna länk för att göra din ansökan

Kontakt
AstraZeneca karin.lyckemalm@astrazeneca.com

Företag
AstraZenecas

Adress
AstraZenecas
43183
43183 1480

Kontorsadress
Pepparredsleden 1

Jobbnummer
4361556

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