Senior Research Scientist - Protein Expression Team
AstraZeneca AB / Kemiingenjörsjobb / Göteborg
2019-10-14
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At AstraZeneca we use scientific excellence as the foundation to drive success of our drug discovery pipeline. Such excellence stems from strong collaboration, clear direction and a focus on applying cutting-edge research to support drug discovery.
An opportunity is now available for a highly motivated Senior Research Scientist to join the Protein Expression Team within Discovery Biology, Discovery Sciences, BioPharmaceuticals R&D in Gothenburg, Sweden. Leading from the bench, you will apply proven skills in molecular biology, recombinant protein expression and cell culture, a passion for investigating scientific questions, combined with strong team working ethics, to drug discovery projects. You will join our team whose remit is to support drug discovery projects globally with delivery of impactful recombinant protein reagents used for disease target identification and validation right through to clinical candidate evaluation.
As part of a team within the Discovery Sciences organisation, you will be working within a vibrant scientific environment to support drug discovery. We push scientific advances in small molecules, oligonucleotides as well as other emerging technologies, always with a view to providing medicines to improve patient care.
Main Duties & Responsibilities
This is a lab-based role, generating bespoke protein reagents to support projects in all phases of the discovery process. The role involves application of leading molecular biology techniques to design expression constructs, make DNA constructs for protein expression, producing recombinant proteins that impact projects, as well as troubleshooting. In addition, you will be required to make a significant contribution to the development and application of novel science to advance our capabilities in the production of molecular biology tools used in early drug discovery.
Essential Requirements
* Ph. D in Molecular Biology, Biotechnology, Cell Biology, Biochemistry or a related discipline, or 5 years of relevant working experience within Biotechnology
* Substantial expertise in cell culture for recombinant protein expression in a variety of eukaryotic cell types, at scales from 1ml to 20L
* Excellent communication skills and an ability to operate effectively in a multi-disciplinary research environment
* Independent analysis and evaluation of complex data and delivery of data to agreed timelines
* Proven ability in providing technical leadership and guidance to others
* Maintain an awareness of relevant scientific and technical advances to help identify opportunities for capability development
Desirable Requirements
* Knowledge in cell culture and recombinant protein expression is essential
* Experience in design of DNA construct for recombinant protein expression is highly desirable
* Practice in use of automation equipment such as liquid handling platforms is desirable
* Experience and knowledge in purification of recombinant expressed proteins
* Good understanding of drug discovery and how to contribute with scientific expertise within own area of expertise to drive project progression
If this sounds like the position and next challenge for you, please apply now!
Please send in your application no later than 4th of November.
For further details around this position you are welcome to contact the recruiting manager Robert Roth (phone +46725826411; email: ).
Additional information about our fantastic city and site:
Our Gothenburg site:
https://www.astrazeneca.com/our-science/gothenburg.htmlLife in Gothenburg:
https://www.movetogothenburg.com/Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2019-10-14ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2019-11-04
Klicka på denna länk för att göra din ansökanFöretagAstrazeneca AB
Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-063370".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Arbetsplats AstraZeneca
Jobbnummer 4885403
Observera att sista ansökningsdag har passerat.