Senior Research Scientist - Molecular biologist

AstraZeneca / Biologjobb / Göteborg
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The department Translational Genomics is looking for the next Senior Researcher who will be part of the Transgenic Models team. We are seeking an expert in the area of precise genome editing and its application in both transgenic animal model generation and cellular engineering. To devise, champion and develop scientific areas aligned with project needs and be an authority in the area of in vivo science and precise genome editing, to lead this from a lab-based perspective and to make significant contributions to the practical delivery of project goals. As a Senior Researcher will be a mentor for the more junior scientists by advising and challenging them and by providing expert advice to aid interpretation of complex data. You will be leading and represent the department at internal interdisciplinary meetings in addition to external meetings and to publish novel science in high impact journals. You will also propose experimental strategies, troubleshoot problems and make significant contributions to the practical delivery of projects in compliance with AstraZeneca corporate responsibility policies and relevant safety standards.

We see that you have good social and communication skills, be collaborative and be a strong team player. Candidates should be able to work independently and have a positive, goal oriented and problem-solving attitude. Good organisational skills are required and you should be comfortable in presenting your results. Excellent English is required, both spoken and written. The following skills are highly desirable:

* Molecular biology expertise and experience of working with mouse embryonic stem cells.
* Working knowledge of the latest precise genome engineering tools both in vitro and in vivo.
* Expertise in the generation and characterization of transgenic animal models
* Generation and use of viral vectors (lentivirus, AAV, Adenovirus) for in vitro and in vivo genetic engineering

Generic component of SRS role descriptor

Accountabilities

* To design genome editing-based strategies and tools required to generate in vivo and in vitro reagents to create disease models
* To perform genetic screens in vitro and in vivo using genome editing tools
* To perform confirmation assays of genetic manipulation and functional validation of engineered animals
* To perform target validation studies in early projects

Minimum experience

You should have a Ph.D. degree or corresponding experience in a relevant scientific discipline with experience in drug discovery or, alternatively, a first degree and significant relevant experience in drug discovery.

For more information about the position please contact:

John Wiseman +46-(0)31-7065417

Welcome with your application no later than 8 February 2018.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2018-01-19

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2018-02-09
Ange följande referens när du ansöker: R-020730
Klicka på denna länk för att göra din ansökan

Kontakt
AstraZeneca daniela.borquez@astrazeneca.com

Företag
AstraZeneca

Adress
AstraZeneca
43183
43183 1480

Kontorsadress
Pepparedsleden 1

Jobbnummer
3914994

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