Senior Research Scientist - Expert on on-DNA synthesis

AstraZeneca AB / Kemistjobb / Göteborg
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Do you have on-DNA synthesis expertise? Are you interested in working on on-DNA chemistry to contribute to the synthesis of new DNA encoded libraries (DEL) and to the development of new on-DNA chemistry? Join us at our DEL synthesis lab in a company where we are committed to lifelong learning, growth and development!

We are seeking a specialized Synthetic Chemist that will play an important part in our iLAB team, focusing on on-DNA synthesis and expanding our DEL platform. You have the opportunity to drive and contribute to the DEL synthesis capabilities in our new lab at AstraZeneca in Gothenburg and deliver on-DNA compounds as well as contribute to the design and production of a proprietary compound collection based on DEL.

Join the team that follows the science unlike anywhere else. This is the place for curious minds. Dig deep into the biology of complex disease and uncover breakthroughs.

What you will do:
This is an exciting role where you will contribute to the expansion of the new DEL synthesis lab capabilities at AstraZeneca Gothenburg. You will design and synthesize on-DNA compounds and DELs. You will also contribute to the continuous improvement of the DEL synthesis platform by evaluating and developing new cutting edge synthetic approaches for on-DNA chemistry.

In your daily work you will troubleshoot laboratory-based problems and make a significant contribution to the delivery of the team. As DEL Chemist, you will maintain access to the best internal and external science and enhance business reputation internally and externally through peer-reviewed publications and oral/poster presentations.

Essential on the role:
You're a chemist with a track record of applying innovative chemistry solutions, with resulting impact in project delivery. You also have:

* Ph.D. in a relevant chemistry discipline, or a Master degree in chemistry with minimum 5 years' experience in synthetic organic chemistry.
* Hands-on experience with on-DNA synthesis and/or synthesis of DNA encoded libraries.
* Expertise in synthetic organic synthesis, retrosynthesis, compound route design, purification and analytical sciences.
* Expertise in parallel chemistry.
* Knowledge of basic molecular biology techniques e.g gel electrophoresis, DNA ligation, PCR.
* Advanced knowledge of modern chemical literature, chemical technologies and applying new ideas to project delivery.

We believe that you enjoy team work and collaborating in an inspiring environment, with the ability to work across scientific fields to reach results. You also share our great passion for science and have a high interest in working with organic chemistry and molecular biology techniques.

Desirable in the role:

* Experience in the development of on-DNA chemistry.
* Knowledge of medicinal chemistry.

Why AstraZeneca Gothenburg?
With more than 2,800 employees from more than 70 different countries, our vibrant Gothenburg site is a truly inspiring place to work. Here, the history and future of scientific breakthrough come together. We believe that the diversity of our people is crucial to bringing new discoveries to life. Thrive in a place where the brightest and most curious minds seamlessly come together in our inclusive environment.

So, what's next? If this sound like your next challenge - welcome to apply today!

Welcome with your application, but send it to us no later than 23rd May, 2023.

For more information about the position please contact Giulia Bergonzini, Director of Chemistry- iLAB, at giulia.bergonzini@astrazeneca.com.

Additional information:
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg: https://www.movetogothenburg.com/
Make a move to Global Gothenburg: https://www.youtube.com/watch?v=c-Iqbb4aw38
About BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2023-05-23
Klicka på denna länk för att göra din ansökan

Arbetsgivarens referens
Arbetsgivarens referens för detta jobb är "R-165300".

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Astrazeneca AB (org.nr 556011-7482)

Arbetsplats
AstraZeneca

Kontakt
AstraZeneca
antonia.reimers@astrazeneca.com

Jobbnummer
7723139

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