Senior Principal Scientist in Material Design

AstraZeneca AB / Kemistjobb / Göteborg
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Are you a curious Senior Principal Scientist seeking a role where your expertise can make an extraordinary impact? Join a place built on innovation and creativity!

In Operations, we have a big ambition: to deliver more medicines to patients, quicker and more affordably. Backed by the investment, leadership and a clear plan to get there, we bring personal dedication and out of the box thinking. We are driven by our commitment to deliver accelerated growth for AstraZeneca and to make people's lives better. It pushes us to keep building on our foundations and progressing as we turn our ever-growing and increasingly complex pipeline from molecule to medicine. Pharmaceutical Technology and Development (PT&D) sits within Operations and is the organization that turns brilliant science into actual medicines that help millions of people.

You'll be part of Oral Product Development, within PT&D, and a delivery focused team where we collaborate to support drug development projects with the goal to impact patients' lives. We focus on the design and development of commercial products and processes and contribute to new product introductions and continuous improvement of launched products. We're developing a wide range of products including e.g. immediate release and controlled release oral dosage forms and applying a variety of manufacturing methods, with focus on continuous manufacturing technologies. To meet the future needs of our portfolio, the introduction of innovative science and technology are key elements, where digital applications, such as data management, modelling and simulations will be integrated in our daily work.

This role will give you the opportunity to in a dynamic and enthusiastic atmosphere, whilst developing and delivering predictive Material Design science to drive the portfolio forward with the right capability and speed.

This role is based at AstraZeneca's vibrant R&D site in Gothenburg, Sweden.

What you'll do

As a Senior Principal Scientist, you will work closely with a team of colleagues in a multi-skilled environment to design, develop and deliver high quality clinical and commercial formulations and processes, using your understanding of existing and new innovative in-silico and experimental technologies. Continuous improvement will be at the core of everything you do, and you will drive the strategy in the Materials Design area to ensure that PT&D will be in the frontline of emerging technologies and tools, including digital transformation. This position will give you the chance to lead discussions and influence key decisions, develop and drive scientific strategy and contribute with wider business scientific strategy, manage and advise key partners including those at senior levels, as well as dealing with cultural differences in a global work setting.

Accountabilities:

* Serves as a senior scientific leader within Oral Product Development and coaches colleagues in the area of material design, emphasizing design right first time principles in a patient-centric environment, driving excellence in transforming oral product development to smarter, cleaner and faster introduction of commercial manufacturing capabilities.
* Passionately drive the scientific knowledge synergy between product design and manufacturing technology, to align and implement key scientific solutions across departments in PT&D to enable continuous manufacturing of drug products. Take responsibility for the quality, reputation, communication and delivery of science in cross-functional teams delivering drug projects.
* Provide strategic direction and advice on new science and technology within the scientific area of Material Design, to actively drive implementation and transfer of and give consultation to methodologies to internal and external parties, including health agencies.
* Continue to develop and drive scientific excellence in the area of Materials Design, within the company as well as with world leading universities, scientific organizations and other industrial partners. Provide disciplinary scientific leadership, coaching and mentorship for scientists.
* Contribute to regulatory documentation, submissions, and defence, applying your understanding of drug development and relevant requirements from medical authorities.

Essential Skills/Experience:

* At least a PhD within Chemistry, Physics, Pharmacy or a similar subject field, ideally with specialism in an area relevant to predictive materials characterisation and design.
* Excellent understanding of theoretical and experimental approaches based on physicochemical engineering and digital design, with emphasis on solids processes.
* Experience in developing and using AI, modelling & simulation tools, multivariate analysis and chemometrics to enhance the pharmaceutical engineering science arena.
* Experience of developing enhanced and robust control strategies to support commercial formulations and manufacturing processes, with successful collaborations with other scientific subject areas and commercial manufacturing sites, and the associated regulatory areas.
* Recognised internally and externally as a scientific and opinion leader in material design with a strong and sustained publication record in this area, for example high impact peer-reviewed publications, patents, and conference presentations.
* Recognised leader that develops people and organisation in line with strategy.

Desirable Skills/Experience:

* A passion for and a broad knowledge of pharmaceutical products and process equipment and technology, including product design and methods for experimental characterization.
* Strong internal and external stakeholder management skills.
* External influence through contacts with various consortia, universities, and agencies.
* Experience in driving complex problem-solving efforts with cross-functional teams.
* Up to date knowledge of the competitive landscape, and emerging science that may impact the business.



We welcome your application no later than 11th November, 2023.

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2023-11-06
Klicka på denna länk för att göra din ansökan

Arbetsgivarens referens
Arbetsgivarens referens för detta jobb är "R-183510".

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Astrazeneca AB (org.nr 556011-7482)

Arbetsplats
AstraZeneca

Kontakt
AstraZeneca
galia.nystrom@astrazeneca.com

Jobbnummer
8222825

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