Scientist

Göteborgs universitet / Apotekarjobb / Göteborg
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At the Department of Internal Medicine and Clinical Nutrition, research in several different areas are conducted, such as endocrinology, hematology, gastroenterology, hypertension, pulmonary medicine and allergology and clinical nutrition. Research is focused on body composition and energy metabolism. Research is conducted in close cooperation with health care at both the Sahlgrenska University Hospital and Mölndal hospital.

Irritable bowel syndrome (IBS) is a functional bowel disorder affecting 10-15 % of the population in the western world. The cause of IBS is unknown but evidence is accumulating that the patients may have a dysregulated mucosal inflammatory reaction due to alterations in the composition of the gut microbiota.

Job assignments

In the proposed project we aim to demonstrate how gut microbiota composition is related to alterations of the gut immune system. Moreover, the project aims to determine how an imbalance in these factors is linked to symptom generation in patients with IBS. The project involves many lab-based techniques such as 16S sequencing of gut microbiota, isolation and culture of human cells and gut microbiota, immunohistochemistry, flow cytometry, and PCR. Large and complex data sets will be generated which will be handled by bioinformatics tools.

Qualifications

The applicant must have a doctoral degree in the appropriate field. Previous experience of research within the area of pathophysiology of IBS is advantageous. Substantial experience of 16S sequencing of gut microbiota, isolation and culture of human cells and flow cytometry is mandatory. Experience of handling large and complex data sets bioinformatics tools, such as R, is a requisite. Previous demonstrated capability of working independently is highly meriting.

Varaktighet, arbetstid
Type of employment: Temporary until 2018-06-30 Extent: 100 % Location: Institute of Medicine, Gothenburg First day of employment: 2017-10-01

Publiceringsdatum
2017-06-20

Så ansöker du
Sista dag att ansöka är 2017-07-10
Ange följande referens när du ansöker: PAR 2017/749

Kontakt
magnus.simren@medicine.gu.se

Företag
Göteborgs universitet

Adress
Göteborgs universitet
Box 100
40530 GÖTEBORG

Kontorsadress
Universitetsplatsen 1

Jobbnummer
3566131

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Scientist

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