Researcher to the Department of Bioinformatics and Genetics
Naturhistoriska Riksmuseet / Kemiingenjörsjobb / Stockholm
2024-03-27
Visa alla kemiingenjörsjobb i Stockholm,
Solna,
Lidingö,
Sundbyberg,
Danderyd eller i
hela Sverige Visa alla jobb hos Naturhistoriska Riksmuseet i Stockholm,
Umeå eller i
hela Sverige The Swedish Museum of Natural History is a government agency with a mandate to promote knowledge, research and interest in our world. It is a prominent research institution and Sweden's largest museum. For more than 200 years, the museum has been collecting specimens and data and conducting research on life on earth. The collections contain more than 11 million plants, animals, fungi, environmental samples, minerals and fossils. All research and knowledge are shared in the exhibitions, Cosmonova and in activities at the museum and digitally.
The Department of Bioinformatics and Genetics consists of the DNA laboratory and a biodiversity informatics group, as well as the Center for PaleoGenetics (CPG), which is a collaboration with Stockholm University. A number of research groups are linked to these activities, which primarily conduct research based on large-scale sequencing of genomes or environmental samples to study biodiversity and evolutionary processes. Research is also conducted in the areas of ecosystem analysis, phylogenetic inference and biodiversity informatics.
WORK TASKS
The work tasks of the project will include DNA extractions from historical/ancient herring material (e.g. finclips, bones) and preparation of WGS libraries using appropriate protocols for degraded DNA. Data processing will involve the use of bioinformatics tools and pipelines suited to ancient DNA data, allowing to examine or correct for DNA damage (e.g. PMDtools, Generode), as well as the use of likelihood approach (e.g. ANGSD) to call SNPs in low coverage genomes. Data analyses will include analyses of genetic differentiation among historical and modern populations using factor analyses (FA) for neutral and non-neural markers. The successful candiate will also examine temporal shifts in genetic loci underlying ecological adaptation using genome scans and detection of outlier loci (e.g. FST). Finally, the project will involve future distribution modelling (e.g.Maxent) using current and future environmental variables and current herring occurrence data as well as genome-informed simulations (e.g. SLIM) to assess the future genomic consequences of warming sea temperature and associated changes in environmental conditions in herring populations. The candidate will then be expected to prepare manuscripts for publication in international high impact journals.
QUALIFICATIONS
Qualification requirements :
• PhD in Zoology.
• Ancient DNA laboratory experience: DNA extraction and library preparation from herring bones.
• Experience in processing of large modern and ancient genomic datasets.
• Experience in genomic analyses (PCA, tests of selection, identification of structural variants).
• Experience in forward simulations in SLIM.
OTHER
We advance our knowledge of the natural world, inspiring to better care of our planet. Our ambition is that the employees of The Swedish Museum of Natural History shall represent the diversity in Sweden and we welcome every applicant.
We have decided upon choices for marketing. Therefore we decline contact with sales agents, recruitment sites and similar.
Ersättning According to agreement.
Så ansöker du Sista dag att ansöka är 2024-04-07
Klicka på denna länk för att göra din ansökan Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "126-2024".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Naturhistoriska Riksmuseet (org.nr 202100-1124),
http://www.nrm.se Arbetsplats Naturhistoriska riksmuseet
Kontakt Head of department
Knud Jønsson
knud.jonsson@nrm.se 08-519 540 11 Jobbnummer 8572347