Researcher to biochemistry and biophysics
Stockholms Universitet / Biologjobb / Stockholm
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hela Sverige at the Department of biochemistry and biophysics. Closing date: 30 June 2017
The Department of Biochemistry and Biophysics is mainly located with the other Departments of Chemistry and Life Sciences in the Arrhenius Laboratories for Natural Sciences, which are situated in the northern part of the University Campus at Frescati. Presently more than 200 people are working at the department, of which around 80 are PhD students, engaged in internationally highly recognized research covering a broad range of subjects. The research projects span across a broad range of topics covering various aspects of structure and function of biological systems. A majority of these topics are centered around biological membranes, where many groups working within this area are part of the Center for Biomembrane Research, which is hosted by the department. The Science for Life Laboratory is also closely linked to the department. The combination of the highly interdisciplinary expertise and research projects at the department is unique in Sweden and also at an international level. This expertise ranges across cell biology, biochemistry, biophysics and theory. For more information about the department, see
www.dbb.su.se/.Main responsibilities
We seek a researcher for developing Escherichia coli strains for the production of recombinant proteins. The bacterium Escherichia coli are by far the most widely used host for the production of recombinant proteins. However, the amounts and the quality of the produced material are often not satisfactory. Therefore, the aim of our laboratory is to develop E. coli strains with improved recombinant protein production characteristics. First, we identify the bottlenecks hampering recombinant protein production in E. coli. Subsequently, based on our knowledge of these bottlenecks we develop E. coli protein production strains using both engineering and evolutionary approaches. In our research, we use a host of different techniques and approaches, incl. advanced bacterial genetics, molecular biology, flow cytometry, fluorescence microscopy, proteomics and whole genome sequencing.
• Schegel et al. Cell Mol Life Sci. 2017 Mar;74(5):891-908. doi: 10.1007/s00018-016-2371-2.
• Hjelm et al. ACS Synth Biol. 2017 Mar 3. doi: 10.1021/acssynbio.6b00321.
• Schlegel et al. Cell Rep. 2015 Mar 10. pii: S2211-1247(15)00175-8.
Qualification requirements
Researchers are appointed primarily for purposes of research and must hold a Swedish doctoral degree or an equivalent degree from another country.
Assessment criteria
Experience indeveloping Escherichia coli strains for the production of recombinant proteins.
Terms of employment
The position involves full-time employment for a maximum of two years, with the possibility of extension. Start date as per agreement.
Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.
Contact
Further information about the position can be obtained from Jan-Willem de Gier, telephone: +46 8 16 2420,
martin.ott@dbb.su.se.
Union representatives
Anqi Lindblom-Ahlm (Saco-S) and Lisbeth Häggberg (Fackförbundet ST and Lärarförbundet), telephone: +46 8 16 20 00 (operator), and
seko@seko.su.se (SEKO).
Application
Apply for the position at Stockholm University's recruitment system by clicking the "Apply" button. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.
Please include the following information with your application
• Your contact details and personal data
• Your highest degree
• Your language skills
• Contact details for 2-3 references
and, in addition, please include the following documents
• Cover letter
• CV - degrees and other completed courses, work experience and a list of publications
• Research proposal (no more than 3 pages) describing:
- why you are interested in the field/project described in the advertisement
- why and how you wish to complete the project
- what makes you suitable for the project in question
• Copy of PhD diploma
• Letters of recommendation (no more than 3 files)
• Publications in support of your application (no more than 3 files).
The instructions for applicants are available at: Instructions - Applicants.
You are welcome to apply!
Stockholms universitet - hos oss ger utbildning och forskning resultat.
Varaktighet, arbetstid
Heltid/ Ej specificerat
Publiceringsdatum2017-06-07ErsättningIndividuell lönesättning
Så ansöker duSista dag att ansöka är 2017-06-21
Klicka på denna länk för att göra din ansökanFöretagStockholms universitet
AdressStockholms universitet
Stockholm
10691 Stockholm
KontorsadressStockholm
Jobbnummer 3540584
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