Researcher in biomedical sciences
Linnéuniversitetet / Sjukgymnastjobb / Kalmar
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The research area and duties
The project is part of our efforts to clarify the role of cooperative phenomena and hierarchical ordering in accounting for high power-output and resistance to stretch of striated muscle in health and disease (e.g. hereditary cardiomyopathies). The project will be carried out in collaboration between A. Månsson and S. Tågerud at Linnaeus University, H. Linke (Lund University, Sweden), D. Rassier (McGill University, Canada) and J.A. Spudich (Stanford University, USA). The focus will be on the development and use of a new experimental set-up for in vitro measurement of forces developed by small ensembles of isolated myosin motors as different length changes are imposed on actin filaments under different conditions (mutated myosin, presence of drugs, etc.). Modelling of the actin-myosin interaction for in-depth interpretation of the experimental results may also be part of the post-doc project. The work will be performed mainly in Kalmar, but extensive interaction with labs of collaborators is expected. The postdoc, whose main focus will be on instrumentation, will work in close collaboration with a PhD student with a focus on biochemistry and biophysics of isolated muscle proteins. Key experimental techniques, in addition to the newly developed force-measuring device, will be fluorescence microscopy and in vitro motility assays.
Qualifications
Applicantsshould have a PhD degree in a subject area of relevance for the project (biophysics, computer science, physics, engineering, etc.). Experience of experimental research work using fluorescence microscopy and biophysical techniques for recording of force and length changes from cells or proteins would be an advantage. The same applies to previous experience of mathematical modelling and development of new experimental techniques. Previous studies of molecular motors and muscle are judged favourably.
Applicants should submit a CV, documentation of exams, a copy of their PhD thesis and reprints if available. A short motivation (
alf.mansson@lnu.se ). See also:
http://lnu.se/personal/alf.manssonHead of Department, Päivy Jokela, tel. +46 (0) 480-44 6071,
paivi.jokela@lnu.seHuman Resources Consultant, Christian Andersson, tel. +46 (0) 470-70 8506,
christian.andersson@lnu.seApply for the position on our website
www.lnu.se Last date for application is: March 4th, 2016. The referencenumber for this position is:2016/813-2.2.1
Please apply by clicking on the "Apply" button at the bottom of the ad. The credentials you invoke must be verified with certification and they must be attached digitally in your application. The application and other documents to be marked with the reference number. All documents cited must be received by the University no later than 24.00 on the closing day.
Varaktighet, arbetstid
Heltid/ Ej specificerat
Publiceringsdatum2016-02-03ErsättningIndividuell, månadslön
Så ansöker duSista dag att ansöka är 2016-03-04
Klicka på denna länk för att göra din ansökanFöretagLinnéuniversitetet
AdressLinnéuniversitetet
Universitetsplatsen 1
35195 Växjö
KontorsadressUniversitetsplatsen 1
Övriga kontaktuppgifter Jobbnummer 2650549
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