Research Scientist Genome Editing
Poolia Göteborg AB / Biologjobb / Göteborg
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hela Sverige Are you motivated to be embedded in an international group working on cutting edge technologies with world leading external collaborators? Then you might be the next Genome Editing Scientist AstraZeneca are looking for. The consulting assignment will start 2018-07-01 and go on to 2018-12-31. Please feel free to contact me with any questions. Warmly welcome to Poolia and AstraZeneca!
about the consultant assignment
The arena:
The precise genome editing group is developing new tools and technologies to facilitate target validation, speedy disease modeling and to evaluate the potential applications and safety of therapeutic genome editing. We are part of the Translational Genomics department where we develop advanced cellular and animal models and we also provide expert support for Next Generation Sequencing and Transcriptome analysis. The candidate will be embedded in an international group working on cutting edge technologies with world leading external collaborators.
Tasks and responsibilities/The role:
• To design and build genome editing-based strategies and tools required to generate in vitro reagents to create disease models
• To develop delivery tools to improve the efficiency of in vivo genome editing
• To perform target validation studies in early projects
Who you are
Minimum requirements:
• Advanced Molecular biology expertise on vector design.
• Functional characterization of gene modified cell lines
• In silico construct design and analysis of genetic perturbation after genome editing
Preferred experience and key factors:
• Experience with synthetic biology tools likes recombination, Gateway cloning and Gibson assembly
• Generation and use of viral vectors (lentivirus, AAV, Adenovirus) and non-viral delivery tools for in vitro and in vivo delivery
• Previous practical expertise with genome editing tools including Cas9/CRISPR, ZFNs and TALENs
• Hands on experience with Next Generation Sequencing library preparation and results analysis
About AstraZeneca
At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people's exceptional skills with those of people from all over the globe.
About Poolia - what's in it for you?
• Collective agreement with Unionen (
https://www.unionen.se/rad-och-stod/om-kollektivavtal) • Strong benefits/offers designed for your need
• Individual career support
• Encouraging life career
• Broad professional network
• Committed consultant manager
Please feel free to contact me if you have any questions before your application.
Looking forward to hearing from you. Warmly welcome to Poolia!
Varaktighet, arbetstid
Heltid Tillsvidare
Publiceringsdatum2018-05-29ErsättningFast månads- vecko- eller timlön
Så ansöker duSista dag att ansöka är 2018-06-04
Ange följande referens när du ansöker: 50495
Klicka på denna länk för att göra din ansökanFöretagPoolia Göteborg AB
AdressPoolia Göteborg AB
Kungsgatan 42
41115 Göteborg
KontorsadressKungsgatan 42
Jobbnummer 4172435
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