Postdoctoral researcher in Biomedicine

Örebro universitet / Högskolejobb / Örebro
2024-05-21


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We are looking for a postdoctoral researcher in Biomedicine for a fixed-term position for 24 months with a possibility of extension at the School of Medical Sciences.

Subject area
The subject area for this position is Medical Sciences, with a special focus on Biomedicine/Host-bacterial interaction.

Background
The position is within the Infection & inflammation research group at Örebro University.

Uropathogenic E. coli (UPEC) is the most common bacteria to cause urinary tract infections (UTI). Post-menopausal women have an increased risk of recurrent UTIs. This is partly explained by reduced estrogenic effects on host defenses against UTIs. Estrogen replacement therapy was shown to be able to reduce the number of episodes of UTI in menopausal women. However, we do not know today if estrogen replacement therapy would help clear an already ongoing UPEC mediated UTI in menopausal women. Current research is mostly focused on how UPEC affects host factors, but not so much is known about how host factors like estrogen affect UPEC virulence.

The overall aim of the project is to investigate the impact of estradiol and testosterone exposure on the virulence of Uropathogenic E. coli and the outcome of an UTI.

Duties and responsibilities
The appointment as a postdoctoral researcher is intended to enable persons who have recently been awarded their doctoral degree to consolidate and develop primarily their research skills.

The applicant will be involved in formulating and testing the scientific hypothesis with experimental work, presentations, and preparation of publications. The applicant will be responsible for research, academic and administrative activities and expected to adapt existing and develop new scientific techniques, test hypothesis and analyse data from a variety of sources.

The applicant will work on in vitro experiments conducted with E. coli, urinary tract epithelium and lymphocytes. In vivo mouse UTI experiment will also be conducted. Basic technical skills like cell culture, ELISA, Western blot, RT-qPCR etc is a requirement. This study will be conducted in close collaboration with two Swedish companies in the life science sector. A very important skill is experience conducting research evaluating the direct effects of hormones on UPEC virulence.

Qualifications and assessment crieteria
To see the job advertisement in its entirety visit https://www.oru.se/english/career/available-positions/.

Information
This is a full-time position for two (or three) years. At Örebro University, salary depends on the successful candidate's qualifications and experience.

For more information about the position, contact Associate Professor Isak Demirel, +46 19 30 3472, e-mail: Isak.demirel@oru.se , Unit head, Associate professor Wessam Melik, e-mail: Wessam.melik@oru.se.

At Örebro University, we expect each member of staff to be open to development and change; take responsibility for their work and performance; demonstrate a keen interest in collaboration and contribute to development; as well as to show respect for others by adopting a constructive and professional approach.

Örebro University actively pursues equal opportunities and gender equality as well as a work environment characterised by openness, trust and respect. We value the qualities that diversity adds to our operations.

Application
The application is made online. Click the button "Apply" to begin the application procedure.

For the application to be complete, the following electronic documents must be included:

• Covering letter, outlining how you believe you can contribute to the continued development of Örebro University
• CV with a relevant description of your overall qualifications and experience
• Account of research qualifications and experience
• Copies of relevant course/degree certificates and references verifying eligibility and criteria met
• Relevant scientific publications (maximum of 10 and in full-text format)

Only documents written in Swedish, English, Norwegian and Danish can be reviewed.
More information for applicants will be found on our career site: https://www.oru.se/english/career/available-positions/applicants-and-external-experts/

The application deadline is 2024-06-04. We look forward to receiving your application!

As we have already made our choices in terms of external collaboration partners and marketing efforts for this recruitment process, we decline any contact with recruitment agencies and advertisers.

As directed by the National Archives of Sweden (Riksarkivet), we are required to deposit one file copy of the application documents, excluding publications, for a period of two years after the appointment decision has gained legal force.

Ersättning
Individuell lönesättning tillämpas.

Så ansöker du
Sista dag att ansöka är 2024-06-04
Klicka på denna länk för att göra din ansökan

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Örebro Universitet (org.nr 202100-2924), http://www.oru.se/

Arbetsplats
Örebro universitet

Jobbnummer
8696293


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