Postdoctoral Researcher in Bioenergetics and Neurosciences
Karolinska Institutet, Institutionen för kvinnors och barns häls / Biologjobb / Solna
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Division
A postdoctoral position is available starting in the winter/spring 2015 at Science for Life Laboratory in Stockholm to study bioenergetics regulation in neurons.
In particular, the successful candidate will investigate interactions between the Na,K ATPase and mitochondria and their role for growth and protection of apoptosis in the "Cell Physics and Pediatric Cell and Molecular Biology" group headed by Professor Hjalmar Brismar (KTH) and Anita Aperia (KI), under the leadership of Dr. Nicolas Fritz.
Duties
Our group uses advanced live imaging techniques combined with various molecular tools and reporters to study the function and mechanisms of regulation of the Na,K ATPase in epithelial and neuronal cells. We have uncovered a new non canonical signaling pathway of the Na,K ATPase that protects form apoptosis (Burlaka et al, JASN 2013, Fontana et al, FEBS letter 2013, Li et al, Nat Comm 2010, Li et al, JASN 2006, Aizman et al, PNAS 2001). The post-doctoral researcher will be an important part of a strong effort to characterize in detail this signaling pathway, with a particular emphasis on the regulation of mitochondrial dynamics and functions and how these are affected by the Na,K-ATPase. Studies will use primary neurons from both rats and transgenic mice.
Entry requirements
We are looking for a highly motivated scientist with a Ph.D. from an appropriate discipline, a strong background in biochemistry and documented experience in ion imaging. The project requires a wide array of techniques; experience of live cell imaging, confocal microscopy, electrophysiology as well as extensive knowledge of the sodium pump would be a clear advantage. The successful candidate is expected to demonstrate a high level of creativity and will work together with a strong team on a very exciting project. The ability to express oneself in speech and writing in English at a high level and interact effectively and work productively in a team will be considered important. Emphasis will be placed on personal suitability.
A person is eligible for a position as postdoctoral research fellow if he or she has obtained a PhD no more than seven years before the last date of employment as postdoc.
The position is available for 1 year with possible extension, from february 2014.
Application process
An employment application must contain the following documents in English or Swedish:
• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)
• Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances
• Verification from the thesis defence committee or the equivalent (only if the thesis defence is scheduled within three months after the application deadline)
The application is to be submitted through the MyNetwork recruitment system.
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Publiceringsdatum2015-01-08Arbetstider och omfattning100%. Tillträde: 1/2 2015 Visstidsanställning
ErsättningMånadslön
Så ansöker duSista dag att ansöka är 2015-01-31
Ange följande referens när du ansöker: 2-4276/2014
Klicka på denna länk för att göra din ansökanKontaktAnita Aperia, Professor
Anita.aperia@ki.seNicolas Fritz, Researcher
Nicolas.fritz@ki.seFacklig kontaktLars Ährlund-Richter, SACO 08 - 5177 34 50,
lars.ahrlund@ki.seChristina Hammarstedt, OFR
christina.hammarstedt@ki.seGunnar Stenberg, SEKO 08-524 880 75
FöretagKarolinska Institutet, Institutionen för kvinnors och barns hälsa
AdressKarolinska Institutet, Institutionen för kvinnors och barns hälsa
Byggnad H2:00, Karolinska Universitetssjukhuset
17176 Stockholm
KontorsadressByggnad H2:00, Karolinska Universitetssjukhuset
Jobbnummer 2119621
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