Postdoctoral fellow in Viral Immunology PAR 2018/1123

Göteborgs universitet / Övriga jobb / Göteborg
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The University of Gothenburg tackles society's challenges with diverse knowledge. 38 000 students and 6 000 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

A postdoctoral research position is available immediately to study B cell and antibody immunodominance in response to influenza A virus infection and vaccination in the newly established Angeletti lab (www.angelettilab.com) at the Department of Microbiology and Immunology, Institute of Biomedicine at the University of Gothenburg.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell - what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

At present, the institute has about 380 employees and approximately 400 million SEK in total assets.

Subject area

Viral Immunology

Subject area description

The goal of the research group is to further elucidate the rules of B cell and antibody immunodominance (Angeletti & Yewdell, Trends in Immunol, 2018) with the overarching goal of improving current influenza vaccination. The postdoctoral project will build on recent mechanistic finding on B cell immunodominance (Angeletti et al., Nature Immunol, 2017) and will aim at further characterizing the influence of pre-existing immunity on subsequent responses and at defining transcriptional signatures driving immunodominance.

Job assignments

The successful candidate will characterize how pre-existing antibodies and memory B cells, with defined specificities, will influence responses to subsequent influenza A virus infection with the aim of focusing antibody responses towards cross-neutralizing epitopes. Further, the candidate will characterize transcriptional signatures of B cells recognizing different antigenic sites on the same molecule. Methods that will be used include in vivo mouse model, flow cytometry, ELISA/ELISPOT, virus neutralization and RNA-sequencing.

Eligibility

An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application.

The qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Assessment

The ideal candidate would have a PhD in immunology/virology with a strong track record of scientific productivity.

Proficiency with in vivo mouse model, multicolor flow cytometry and other basic immunological techniques (ELISA, ELISPOT, etc) is a must. Experience within virology and RNA-sequencing is preferred but not essential.

The successful candidate is expected to be highly motivated, capable to plan and execute experiments independently and to actively contribute scientifically to the group. Fluency in spoken and written English is essential.

Employment

The employment is full time and temporary, two years, with placement at the Institute of Biomedicine.

For further information:

Please contact research fellow Davide Angeletti, phone: +46 31 786 6324, e-mail: davide.angeletti@gu.se

Unions

Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

How to apply

In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The application should contain:

• A cover letter giving a brief description of previous research experience, and a motivation to why you are applying
• A CV including a list of publications
• Proof of completed PhD
• Contact details of two references

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.



In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

Varaktighet, arbetstid
Temporary employment 2 years Full time

Publiceringsdatum
2018-08-23

Ersättning
Salary is determined on an individual basis.

Så ansöker du
Sista dag att ansöka är 2018-09-23
Klicka på denna länk för att göra din ansökan

Företag
Göteborgs universitet

Adress
Göteborgs universitet
Box 440
40530 Göteborg

Kontorsadress
Medicinaregatan 7A

Jobbnummer
4305660

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